Doizi Steeve, Letendre Julien, Bonneau Claire, Gil Diez de Medina Sixtina, Traxer Olivier
Department of Urology, Tenon Hospital, Paris, France; Pierre and Marie Curie University, Tenon Hospital, Paris, France.
Department of Urology, Tenon Hospital, Paris, France.
Urology. 2015 Jan;85(1):38-44. doi: 10.1016/j.urology.2014.08.028. Epub 2014 Oct 29.
To compare the efficacy and the safety of flexible ureterorenoscopy (f-URS) in the treatment of kidney stones according to the body mass index (BMI), which seems to be less influenced by weight compared with shock wave lithotripsy and percutaneous nephrolithotomy.
We conducted a retrospective monocentric study in patients with a known BMI who underwent an f-URS for kidney stones between 2006 and 2008. Success rates in the obese patients (OP) group (BMI ≥30 kg/m(2)) were compared with success rates in the normal weight patients (NWP) control group (BMI <25 kg/m(2)). Patients with a BMI ≥40 kg/m(2) were defined as morbidly obese patients (MOP), a subgroup of the OP group. The success was defined as a stone-free status (no or ≤2 mm residual stone) at the time of control, 3 months after the procedure assessed by kidneys-ureters-bladder radiography coupled with ultrasound (only in NWP with radiopaque stones), or computed tomography-scan.
A total of 327 procedures were performed, including 97 f-URS in 87 OP (including 14 procedures in 13 MOP) and 230 procedures for 188 NWP. The overall success rate was 67.4% and 68% in the NWP and OP, respectively; P = .91 (71.4% in the MOP subgroup). Success rates decreased with an increasing stone size without any differences between the groups. Regardless of location and stone size (<10, 10-20, >20 mm), there was no statistical difference in the success rate. Postoperative morbidity was similar in both groups and occurred in 2.44% of cases.
f-URS for kidney stones resulted in similar outcomes in NWP and OP, and even MOP, regardless of stone size and location and with equivalent morbidity.
根据体重指数(BMI)比较软性输尿管肾镜检查(f-URS)治疗肾结石的疗效和安全性,与冲击波碎石术和经皮肾镜取石术相比,f-URS似乎受体重影响较小。
我们对2006年至2008年间因肾结石接受f-URS且已知BMI的患者进行了一项回顾性单中心研究。将肥胖患者(OP)组(BMI≥30kg/m²)的成功率与正常体重患者(NWP)对照组(BMI<25kg/m²)的成功率进行比较。BMI≥40kg/m²的患者被定义为病态肥胖患者(MOP),是OP组的一个亚组。成功定义为在术后3个月复查时结石清除状态(无残留结石或残留结石≤2mm),通过肾脏-输尿管-膀胱造影联合超声检查(仅适用于有不透X线结石的NWP)或计算机断层扫描评估。
共进行了327例手术,其中87例OP患者接受了97次f-URS(包括13例MOP患者的14次手术),188例NWP患者接受了230次手术。NWP组和OP组的总体成功率分别为67.4%和68%;P = 0.91(MOP亚组为71.4%)。成功率随结石大小增加而降低,两组间无差异。无论结石位置和大小(<10、10 - 20、>20mm)如何,成功率均无统计学差异。两组术后发病率相似,为2.44%。
无论结石大小、位置如何,f-URS治疗肾结石在NWP、OP甚至MOP患者中都能取得相似的结果,且发病率相当。