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[体重指数对肾结石输尿管镜检查结果的影响]

[Effect of the body mass index on outcomes of ureterorenoscopy for renal stones].

作者信息

Schott F, Knipper S, Orywal A K, Gross A J, Netsch C

机构信息

Abteilung für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22291, Hamburg, Deutschland.

出版信息

Urologe A. 2016 Nov;55(11):1462-1469. doi: 10.1007/s00120-016-0132-3.

DOI:10.1007/s00120-016-0132-3
PMID:27272003
Abstract

BACKGROUND

Purpose of this work is to compare the outcome of ureterorenoscopy (URS) with regard to stone-free rates (SFR) and complication rates (CR) in patients with different body mass index (BMI) scores for the treatment of kidney stones.

MATERIALS AND METHODS

A retrospective chart review of all patients with known BMI, who underwent URS for kidney stones between 2006 and 2012 at our institution, was performed (n = 556 patients). The SFR and CR of obese patients were compared to overweight and normal weight patients.

RESULTS

Mean age was 52.51 years and the average BMI 27.74 kg/m. Of the patients, 34.2 % had normal weight (22.59 ± 1.91 kg/m), 39.6 % were overweight (27.30 ± 1.42 kg/m), and 26.3 % were obese (35.09 ± 5.93 kg/m). The mean ASA score differed significantly between normal weight (1.99 ± 0.57), overweight (2.03 ± 0.62), and obese (2.22 ± 0.63) patients (p ≤ 0.036). The mean stone size was 8.51 ± 6.84 mm and the mean number of stones per patient 1.9 ± 2.41, whereby the differences between groups was not significant. There were no differences between the groups regarding the use of preoperative (94.8 %) and postoperative ureteral stents (60.3 %), the Ho:YAG laser (33.6 %), the use of flexible (16.2 %) or semirigid/flexible URS (59.4 %), and the mean operative time (52.04 ± 34.55 min). There were no differences in the SFR for the upper (90 %), mid (94.7 %), and lower pole (90.2 %), multiple location (68.6 %) or the total SFR (86.3 %). Total SFR of 95.7, 88.4, and 73.7 % for urinary calculi < 5 mm, 5-9 mm, and ≥ 10 mm, respectively, were found and the differences between the patient groups was not significant. The CR was 10.4 % (differences between the patient groups not significant).

CONCLUSION

URS is an appropriate treatment for renal stones with high SFR and low CR regardless of patient's BMI.

摘要

背景

本研究旨在比较不同体重指数(BMI)评分的肾结石患者接受输尿管肾镜检查(URS)后的结石清除率(SFR)和并发症发生率(CR)。

材料与方法

对2006年至2012年在我院接受URS治疗肾结石且已知BMI的所有患者进行回顾性病历审查(n = 556例患者)。将肥胖患者的SFR和CR与超重和正常体重患者进行比较。

结果

平均年龄为52.51岁,平均BMI为27.74kg/m²。患者中,34.2%体重正常(22.59±1.91kg/m²),39.6%超重(27.30±1.42kg/m²),26.3%肥胖(35.09±5.93kg/m²)。正常体重(1.99±0.57)、超重(2.03±0.62)和肥胖(2.22±0.63)患者的平均美国麻醉医师协会(ASA)评分差异有统计学意义(p≤0.036)。平均结石大小为8.51±6.84mm,每位患者的平均结石数量为1.9±2.41,各组之间差异无统计学意义。在术前(94.8%)和术后输尿管支架的使用(60.3%)、钬:钇铝石榴石(Ho:YAG)激光(33.6%)、软性(16.2%)或半硬性/软性URS的使用(59.4%)以及平均手术时间(52.04± 34.55分钟)方面,各组之间无差异。上极(90%)、中极(94.7%)和下极(90.2%)、多部位( 68.6%)或总SFR(86.3%)的SFR无差异。分别发现<5mm、5 - 9mm和≥10mm尿结石患者的总SFR为95.7%、88.4%和73.7%,患者组之间差异无统计学意义。CR为10.4%(患者组之间差异无统计学意义)。

结论

无论患者BMI如何,URS都是治疗肾结石的一种合适方法,具有高SFR和低CR。

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本文引用的文献

1
Comparative study of the treatment of renal stones with flexible ureterorenoscopy in normal weight, obese, and morbidly obese patients.正常体重、肥胖和病态肥胖患者输尿管软镜治疗肾结石的对比研究
Urology. 2015 Jan;85(1):38-44. doi: 10.1016/j.urology.2014.08.028. Epub 2014 Oct 29.
2
Impact of surgical experience on stone-free rates of ureteroscopy for single urinary calculi of the upper urinary tract: a matched-paired analysis of 600 patients.手术经验对上尿路单发尿石症输尿管镜取石率的影响:600例患者的配对分析
J Endourol. 2015 Jan;29(1):78-83. doi: 10.1089/end.2014.0301.
3
Effect of the body mass index on outcomes of flexible ureterorenoscopy.
体重指数对软性输尿管镜检查结果的影响。
Urolithiasis. 2013 Nov;41(6):499-504. doi: 10.1007/s00240-013-0590-7. Epub 2013 Jul 23.
4
A multicenter comparison of the safety and effectiveness of ureteroscopic laser lithotripsy in obese and normal weight patients.多中心比较肥胖和正常体重患者输尿管镜激光碎石术的安全性和有效性。
J Endourol. 2013 Jun;27(6):710-4. doi: 10.1089/end.2012.0605.
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The impact of body mass index on the outcomes of retrograde intrarenal stone surgery.体重指数对逆行性肾内结石手术结局的影响。
Urology. 2013 Mar;81(3):517-21. doi: 10.1016/j.urology.2012.12.008.
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Clavien classification of semirigid ureteroscopy complications: a prospective study.半刚性输尿管镜并发症的 Clavien 分类:一项前瞻性研究。
Urology. 2012 Nov;80(5):995-1001. doi: 10.1016/j.urology.2012.05.047.
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Impact of preoperative ureteral stenting on stone-free rates of ureteroscopy for nephroureterolithiasis: a matched-paired analysis of 286 patients.术前输尿管支架置入对输尿管镜治疗肾输尿管结石结石清除率的影响:286 例配对分析。
Urology. 2012 Dec;80(6):1214-9. doi: 10.1016/j.urology.2012.06.064. Epub 2012 Oct 18.
8
The CROES percutaneous nephrolithotomy global study: the influence of body mass index on outcome.《CROES 经皮肾镜取石术全球研究:体质量指数对结局的影响》。
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Prevalence of kidney stones in the United States.美国肾结石的患病率。
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Safety and efficacy of ureteroscopic lithotripsy for stone disease in obese patients: a systematic review of the literature.经尿道输尿管镜碎石术治疗肥胖患者结石病的安全性和疗效:文献系统评价。
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