Qureshi Kamran, Al-Osaimi Abdullah M S
Division of Hepatology, Department of Medicine, Temple University Health System, Temple University School of Medicine, 3440 North Broad Street, Kresge West, Room 209, Philadelphia, PA 19140, USA.
Division of Hepatology, Department of Medicine, Temple University Health System, Temple University School of Medicine, 3440 North Broad Street, Kresge West, Room 216, Philadelphia, PA 19140, USA.
Gastroenterol Clin North Am. 2014 Dec;43(4):835-47. doi: 10.1016/j.gtc.2014.08.012. Epub 2014 Sep 20.
Gastric antral vascular ectasia (GAVE) and portal hypertensive gastropathy (PHG) are important causes of chronic gastrointestinal bleeding. These gastric mucosal lesions are mostly diagnosed on upper endoscopy and can be distinguished based on their appearance or location in the stomach. In some situations, especially in patients with liver cirrhosis and portal hypertension, a diffuse pattern and involvement of gastric mucosa are seen with both GAVE and severe PHG. The diagnosis in such cases is hard to determine on visual inspection, and thus, biopsy and histologic evaluation can be used to help differentiate GAVE from PHG.
胃窦血管扩张症(GAVE)和门脉高压性胃病(PHG)是慢性胃肠道出血的重要原因。这些胃黏膜病变大多通过上消化道内镜检查诊断,可根据其在胃内的外观或位置进行区分。在某些情况下,尤其是在肝硬化和门脉高压患者中,GAVE和严重的PHG均可出现胃黏膜弥漫性病变。在此类病例中,仅凭视觉检查很难做出诊断,因此,活检和组织学评估有助于鉴别GAVE和PHG。