婴儿猝死综合征的感染性病因。
Infectious causes of sudden infant death syndrome.
作者信息
Alfelali Mohammad, Khandaker Gulam
机构信息
National Centre for Immunisation Research and Surveillance (NCIRS), The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Department of Family and Community Medicine, Faculty of Medicine in Rabigh, King Abdulaziz University, Saudi Arabia.
National Centre for Immunisation Research and Surveillance (NCIRS), The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia; Centre for Perinatal Infection Research, The Children's Hospital at Westmead and The University of Sydney, Sydney, NSW, Australia; Marie Bashir Institute for Infectious Diseases and Biosecurity Institute (MBI), University of Sydney, Sydney, NSW, Australia.
出版信息
Paediatr Respir Rev. 2014 Dec;15(4):307-11. doi: 10.1016/j.prrv.2014.09.004. Epub 2014 Sep 19.
Investigators have long suspected the role of infection in sudden infant death syndrome (SIDS). Evidence of infectious associations with SIDS is accentuated through the presence of markers of infection and inflammation on autopsy of SIDS infants and isolates of some bacteria and viruses. Several observational studies have looked into the relation between seasonality and incidence of SIDS, which often showed a winter peak. These all may suggest an infectious aetiology of SIDS. In this review we have summarised the current literature on infectious aetiologies of SIDS by looking at viral, bacterial, genetic and environmental factors which are believed to be associated with SIDS.
长期以来，研究人员一直怀疑感染在婴儿猝死综合征（SIDS）中所起的作用。通过对SIDS婴儿进行尸检时发现感染和炎症的标志物以及分离出一些细菌和病毒，更突显了感染与SIDS之间存在关联的证据。多项观察性研究探讨了季节性与SIDS发病率之间的关系，这些研究常常显示冬季发病率达到峰值。所有这些都可能提示SIDS的感染病因。在本综述中，我们通过研究被认为与SIDS相关的病毒、细菌、遗传和环境因素，总结了当前关于SIDS感染病因的文献。
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