在使用心室辅助装置进行最长时间支持后的心脏移植。
Heart transplantation after longest-term support with ventricular assist devices.
作者信息
Hetzer Roland, Miera Oliver, Photiadis Joachim, Hennig Edwald, Knosalla Christoph, Delmo Walter Eva Maria
机构信息
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum, Berlin, Germany.
Department of Pediatric Cardiology and Congenital Heart Diseases, Deutsches Herzzentrum, Berlin, Germany.
出版信息
Ann Thorac Surg. 2014 Nov;98(5):1814-5. doi: 10.1016/j.athoracsur.2013.12.052. Epub 2014 Oct 30.
The use of mechanical circulatory support devices to keep patients alive until transplantation has become essential in the face of an increasing organ shortage. We report successful heart transplantations after 841 days of left ventricular assist device (LVAD) support in a child with hypoplastic left heart syndrome, and after 547 days of biventricular assist device (BVAD) support in another child with cardiomyopathy. To our knowledge, this report is the first on the longest-term (841 days) LVAD and the longest-term (547 days) BVAD support in children who were mobile and awake during the support, as a most effective bridge to heart transplantation.
面对日益严重的器官短缺问题，使用机械循环支持设备维持患者生命直至进行移植已变得至关重要。我们报告了两例成功的心脏移植案例，一例是患有左心发育不全综合征的儿童在左心室辅助装置（LVAD）支持841天后接受心脏移植，另一例是患有心肌病的儿童在双心室辅助装置（BVAD）支持547天后接受心脏移植。据我们所知，本报告首次报道了在支持期间能够活动且清醒的儿童中最长时间（841天）的LVAD支持和最长时间（547天）的BVAD支持，作为心脏移植最有效的桥梁。
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