阴沟肠杆菌GGT036的全基因组序列：一种耐糠醛的土壤细菌。

Complete genome sequence of Enterobacter cloacae GGT036: a furfural tolerant soil bacterium.

作者信息

Gong Gyeongtaek, Um Youngsoon, Park Tai Hyun, Woo Han Min

机构信息

Clean Energy Research Center, Korea Institute of Science and Technology, Hwarang-ro 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea; Interdisciplinary Program of Bioengineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-744, Republic of Korea.

Clean Energy Research Center, Korea Institute of Science and Technology, Hwarang-ro 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Clean Energy and Chemical Engineering, Korea University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.

出版信息

J Biotechnol. 2015 Jan 10;193:43-4. doi: 10.1016/j.jbiotec.2014.11.012. Epub 2014 Nov 22.

DOI:10.1016/j.jbiotec.2014.11.012

PMID:25444880

Abstract

Enterobacter cloacae is a facultative anaerobic bacterium to be an important cause of nosocomial infection. However, the isolated E. cloacae GGT036 showed higher furfural-tolerant cellular growth, compared to industrial relevant strains such as Escherichia coli and Corynebacterium glutamicum. Here, we report the complete genome sequence of E. cloacae GGT036 isolated from Mt. Gwanak, Seoul, Republic of Korea. The genomic DNA sequence of E. cloacae GGT036 will provide valuable genetic resources for engineering of industrially relevant strains being tolerant to cellular inhibitors present in lignocellulosic hydrolysates.

摘要

阴沟肠杆菌是一种兼性厌氧菌，是医院感染的重要原因。然而，与工业相关菌株如大肠杆菌和谷氨酸棒杆菌相比，分离出的阴沟肠杆菌GGT036表现出更高的耐糠醛细胞生长能力。在此，我们报告从韩国首尔冠岳山分离出的阴沟肠杆菌GGT036的完整基因组序列。阴沟肠杆菌GGT036的基因组DNA序列将为工程改造耐受木质纤维素水解产物中存在的细胞抑制剂的工业相关菌株提供有价值的遗传资源。