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心血管健康筛查与死亡率、临床结局及医疗保健成本的关联:一项全国性队列研究。

Association of cardiovascular health screening with mortality, clinical outcomes, and health care cost: a nationwide cohort study.

作者信息

Lee Hyejin, Cho Juhee, Shin Dong Wook, Lee Seung-Pyo, Hwang Seung-Sik, Oh Juhwan, Yang Hyung-Kook, Hwang Soo-Hee, Son Ki Young, Chun So Hyun, Cho BeLong, Guallar Eliseo

机构信息

Department of Family Medicine & Health Promotion Center, Seoul National University Hospital, Republic of Korea.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, USA; Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea.

出版信息

Prev Med. 2015 Jan;70:19-25. doi: 10.1016/j.ypmed.2014.11.007. Epub 2014 Nov 20.

DOI:10.1016/j.ypmed.2014.11.007
PMID:
25445334
Abstract

OBJECTIVE

To determine whether a cardiovascular disease (CVD) health screening program is associated with CVD-related health conditions, incidence of cardiovascular events, mortality, healthcare utilization, and costs.

METHODS

Cohort study of a 3% random sample of all Korea National Health Insurance members 40years of age or older and free of CVD or CVD-related health conditions was conducted. A total 443,337 study participants were followed-up from January 1, 2005 through December 31, 2010.

RESULTS

In primary analysis, the hazard ratios for CVD mortality, all-cause mortality, incident composite CVD events, myocardial infarction, cerebral infarction, and cerebral hemorrhage comparing participants who attended a screening exam during 2003-2004 compared to those who did not were 0.58 (95% CI: 0.53-0.63), 0.62 (95% CI: 0.60-0.64), 0.82 (95% CI: 0.78-0.85), 0.84 (95% CI: 0.75-0.93), 0.84 (95% CI: 0.79-0.89), and 0.73 (95% CI: 0.67-0.80), respectively. Screening attenders had higher rates of newly diagnosed hypertension, diabetes mellitus, and dyslipidemia, lower inpatient days of stay and cost, and lower outpatient cost compared to non-attenders.

CONCLUSIONS

Participation in CVD health screening was associated with lower rates of CVD, all-cause mortality, and CVD events, higher detection of CVD-related health conditions, and lower healthcare utilization and costs.

摘要

目的

确定心血管疾病(CVD)健康筛查项目是否与CVD相关健康状况、心血管事件发生率、死亡率、医疗保健利用情况及成本有关。

方法

对韩国国民健康保险中所有40岁及以上且无CVD或CVD相关健康状况的成员进行3%的随机抽样队列研究。从2005年1月1日至2010年12月31日对总共443,337名研究参与者进行了随访。

结果

在初步分析中,与未参加筛查的参与者相比,2003 - 2004年期间参加筛查的参与者的CVD死亡率、全因死亡率、复合CVD事件发生率、心肌梗死、脑梗死和脑出血的风险比分别为0.58(95%置信区间:0.53 - 0.63)、0.62(95%置信区间:0.60 - 0.64)、0.82(95%置信区间:0.78 - 0.85)、0.84(95%置信区间:0.75 - 0.93)、0.84(95%置信区间:0.79 - 0.89)和0.73(95%置信区间:0.67 - 0.80)。与未参加者相比,参加筛查者新诊断高血压、糖尿病和血脂异常的比例更高,住院天数和费用更低,门诊费用也更低。

结论

参与CVD健康筛查与较低的CVD发病率、全因死亡率和CVD事件发生率、较高的CVD相关健康状况检出率以及较低的医疗保健利用和成本有关。

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