肺癌。非小细胞肺癌中铂类化疗用多少合适？
Lung cancer. How much platinum-based chemotherapy is enough in NSCLC?
机构信息
Oncology Department, Centre Hospitalier Universitaire Vaudois (CHUV), Rue du Bugnon 27, 1011 Lausanne, Switzerland.
Roswell Park Cancer Institute, Elm &Carlton Streets, Buffalo, NY 14263, USA.
出版信息
Nat Rev Clin Oncol. 2015 Jan;12(1):8-10. doi: 10.1038/nrclinonc.2014.212. Epub 2014 Dec 2.
PMID:25445558
Abstract
With no large randomized phase III trials to provide definitive answers, the ideal number of platinum-based chemotherapy cycles in patients with advanced non-small-cell lung cancer has long been unclear. Most guidelines recommend a maximum of 4–6 cycles. Rossi and colleagues now suggest that four chemotherapy cycles is the optimal regimen.
摘要
由于没有大型随机 III 期试验提供明确的答案，因此晚期非小细胞肺癌患者接受铂类为基础的化疗周期的理想数量一直不清楚。大多数指南建议最多进行 4-6 个周期。Rossi 及其同事现在提出，4 个化疗周期是最佳方案。
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