Escamilla Roger
Hôpital Larrey, pôle respiratoire, 24, chemin de Pouvourville, 31059 Toulouse cedex 9, France.
Presse Med. 2014 Dec;43(12 Pt 1):1381-6. doi: 10.1016/j.lpm.2014.05.018. Epub 2014 Oct 31.
COPD is a respiratory disease associated with multiple extrapulmonary comorbidities: cardiovascular diseases, osteoporosis, depression and psychological disorders are the most prevalent. Comorbidities, especially ischemic heart disease, represent a major cause of morbidity and mortality in COPD patients. The putative link between COPD and comorbidities could be the low-grade systemic inflammation, which is common in COPD. The presence of multiple comorbidities has a strong impact on the management of COPD patients.
慢性阻塞性肺疾病（COPD）是一种与多种肺外合并症相关的呼吸系统疾病：心血管疾病、骨质疏松症、抑郁症和心理障碍最为常见。合并症，尤其是缺血性心脏病，是COPD患者发病和死亡的主要原因。COPD与合并症之间可能的联系是低度全身炎症，这在COPD中很常见。多种合并症的存在对COPD患者的管理有很大影响。
