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[苏联北欧地区居民垂体-肾上腺系统状况及肾上腺的功能形态学]

[Status of the hypophyseo-adrenal system and functional morphology of the adrenal glands in residents of Northern European areas of the USSR].

作者信息

Sukhanov S G, Tkachev A V

出版信息

Arkh Patol. 1989;51(4):58-62.

PMID:2545185
Abstract

Serum corticotropin and cortisol levels were measured in 20-40-year old healthy residents (144 males and 361 females) in the North. A functional Synacthen Depot test was performed in 5 volunteers. The adrenal glands from 56 males and 8 females of the same age who had died from accidents were pathohistologically and stereometrically examined. The signs of functional tension were established in the pituitary-adrenal cortex system. The Synacthen Depot test determined sufficient potentials of the organ to show responses to specific stimulation. Morphologically, a number of changes were found, which might be regarded as a prerequisite to the development of functional and pathological disturbances in the above-mentioned link of the endocrine system.

摘要

对北方地区20至40岁的健康居民(144名男性和361名女性)测量了血清促肾上腺皮质激素和皮质醇水平。对5名志愿者进行了长效合成促肾上腺皮质激素释放激素功能试验。对56名男性和8名同年龄段死于事故的女性的肾上腺进行了病理组织学和立体测量检查。垂体-肾上腺皮质系统出现了功能紧张的迹象。长效合成促肾上腺皮质激素释放激素功能试验确定该器官有足够的潜力对特定刺激做出反应。在形态学上,发现了一些变化,这些变化可能被视为内分泌系统上述环节功能和病理紊乱发展的先决条件。

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