Foruria A M, Lawrence T M, Augustin S, Morrey B F, Sanchez-Sotelo J
Department of Orthopaedic Surgery, Shoulder and Elbow Surgery Unit, Fundación Jiménez Díaz, Avda Reyes Católicos, 2, Madrid 28040, Spain.
University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, West Midlands CV2 2DX, UK.
Bone Joint J. 2014 Dec;96-B(12):1681-7. doi: 10.1302/0301-620X.96B12.34091.
We retrospectively reviewed 89 consecutive patients (45 men and 44 women) with a mean age at the time of injury of 58 years (18 to 97) who had undergone external fixation after sustaining a unilateral fracture of the distal humerus. Our objectives were to determine the incidence of heterotopic ossification (HO); identify risk factors associated with the development of HO; and characterise the location, severity and resultant functional impairment attributable to the presence of HO. HO was identified in 37 elbows (42%), mostly around the humerus and along the course of the medial collateral ligament. HO was hazy immature in five elbows (13.5%), mature discrete in 20 (54%), extensive mature in 10 (27%), and complete bone bridges were present in two elbows (5.5%). Mild functional impairment occurred in eight patients, moderate in 27 and severe in two. HO was associated with less extension (p = 0.032) and less overall flexion-to-extension movement (p = 0.022); the flexion-to-extension arc was < 100º in 21 elbows (57%) with HO compared with 18 elbows (35%) without HO (p = 0.03). HO was removed surgically in seven elbows. The development of HO was significantly associated with sustaining a head injury (p = 0.015), delayed internal fixation (p = 0.027), the method of fracture fixation (p = 0.039) and the use of bone graft or substitute (p = 0.02).HO continues to be a substantial complication after internal fixation for distal humerus fractures.
我们回顾性分析了89例连续的患者(45例男性和44例女性),这些患者平均受伤年龄为58岁(18至97岁),均因单侧肱骨远端骨折接受了外固定治疗。我们的目的是确定异位骨化(HO)的发生率;识别与HO发生相关的危险因素;并描述HO的位置、严重程度以及由此导致的功能障碍。在37例肘部(42%)中发现了HO,主要位于肱骨周围及内侧副韧带走行处。5例肘部(13.5%)的HO为模糊未成熟型,20例(54%)为成熟离散型,10例(27%)为广泛成熟型,2例肘部(5.5%)存在完整骨桥。8例患者出现轻度功能障碍,27例为中度,2例为重度。HO与伸展减少(p = 0.032)和整体屈伸活动减少(p = 0.022)相关;与无HO的18例肘部(35%)相比,21例有HO的肘部(57%)屈伸弧<100°(p = 0.03)。7例肘部的HO接受了手术切除。HO的发生与头部受伤(p = 0.015)、内固定延迟(p = 0.027)、骨折固定方法(p = 0.039)以及使用骨移植或替代物(p = 0.02)显著相关。对于肱骨远端骨折,HO仍然是内固定术后的一个严重并发症。