• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肱骨远端骨折手术后的异位骨化。

Heterotopic ossification after surgery for distal humeral fractures.

作者信息

Foruria A M, Lawrence T M, Augustin S, Morrey B F, Sanchez-Sotelo J

机构信息

Department of Orthopaedic Surgery, Shoulder and Elbow Surgery Unit, Fundación Jiménez Díaz, Avda Reyes Católicos, 2, Madrid 28040, Spain.

University Hospitals Coventry and Warwickshire, Clifford Bridge Road, Coventry, West Midlands CV2 2DX, UK.

出版信息

Bone Joint J. 2014 Dec;96-B(12):1681-7. doi: 10.1302/0301-620X.96B12.34091.

DOI:10.1302/0301-620X.96B12.34091
PMID:25452373
Abstract

We retrospectively reviewed 89 consecutive patients (45 men and 44 women) with a mean age at the time of injury of 58 years (18 to 97) who had undergone external fixation after sustaining a unilateral fracture of the distal humerus. Our objectives were to determine the incidence of heterotopic ossification (HO); identify risk factors associated with the development of HO; and characterise the location, severity and resultant functional impairment attributable to the presence of HO. HO was identified in 37 elbows (42%), mostly around the humerus and along the course of the medial collateral ligament. HO was hazy immature in five elbows (13.5%), mature discrete in 20 (54%), extensive mature in 10 (27%), and complete bone bridges were present in two elbows (5.5%). Mild functional impairment occurred in eight patients, moderate in 27 and severe in two. HO was associated with less extension (p = 0.032) and less overall flexion-to-extension movement (p = 0.022); the flexion-to-extension arc was < 100º in 21 elbows (57%) with HO compared with 18 elbows (35%) without HO (p = 0.03). HO was removed surgically in seven elbows. The development of HO was significantly associated with sustaining a head injury (p = 0.015), delayed internal fixation (p = 0.027), the method of fracture fixation (p = 0.039) and the use of bone graft or substitute (p = 0.02).HO continues to be a substantial complication after internal fixation for distal humerus fractures.

摘要

我们回顾性分析了89例连续的患者(45例男性和44例女性),这些患者平均受伤年龄为58岁(18至97岁),均因单侧肱骨远端骨折接受了外固定治疗。我们的目的是确定异位骨化(HO)的发生率;识别与HO发生相关的危险因素;并描述HO的位置、严重程度以及由此导致的功能障碍。在37例肘部(42%)中发现了HO,主要位于肱骨周围及内侧副韧带走行处。5例肘部(13.5%)的HO为模糊未成熟型,20例(54%)为成熟离散型,10例(27%)为广泛成熟型,2例肘部(5.5%)存在完整骨桥。8例患者出现轻度功能障碍,27例为中度,2例为重度。HO与伸展减少(p = 0.032)和整体屈伸活动减少(p = 0.022)相关;与无HO的18例肘部(35%)相比,21例有HO的肘部(57%)屈伸弧<100°(p = 0.03)。7例肘部的HO接受了手术切除。HO的发生与头部受伤(p = 0.015)、内固定延迟(p = 0.027)、骨折固定方法(p = 0.039)以及使用骨移植或替代物(p = 0.02)显著相关。对于肱骨远端骨折,HO仍然是内固定术后的一个严重并发症。

相似文献

1
Heterotopic ossification after surgery for distal humeral fractures.肱骨远端骨折手术后的异位骨化。
Bone Joint J. 2014 Dec;96-B(12):1681-7. doi: 10.1302/0301-620X.96B12.34091.
2
Risk factors for development of heterotopic ossification of the elbow after fracture fixation.骨折固定后肘部异位骨化的发展风险因素。
J Shoulder Elbow Surg. 2012 Nov;21(11):1550-4. doi: 10.1016/j.jse.2012.05.040. Epub 2012 Sep 2.
3
Clinically relevant heterotopic ossification after elbow fracture surgery: a risk factors study.肘关节骨折术后临床相关的异位骨化:一项危险因素研究。
Orthop Traumatol Surg Res. 2015 Apr;101(2):209-13. doi: 10.1016/j.otsr.2014.10.021. Epub 2015 Feb 18.
4
Surgical resection of severe heterotopic ossification after open reduction and internal fixation of acetabular fractures: a case series of 18 patients.髋臼骨折切开复位内固定术后严重异位骨化的手术切除:18例病例系列
Injury. 2014 Oct;45(10):1604-10. doi: 10.1016/j.injury.2014.05.018. Epub 2014 May 27.
5
Risk factors for heterotopic ossification in operatively treated proximal humeral fractures.手术治疗肱骨近端骨折后异位骨化的危险因素。
Bone Joint J. 2020 Apr;102-B(4):539-544. doi: 10.1302/0301-620X.102B4.BJJ-2019-1510.R1.
6
Severity of heterotopic ossification in patients following surgery for hip fracture: a retrospective observational study.髋关节骨折手术后患者异位骨化的严重程度:一项回顾性观察研究。
BMC Musculoskelet Disord. 2019 Jul 27;20(1):348. doi: 10.1186/s12891-019-2725-7.
7
Complications of Early Versus Delayed Total Elbow Arthroplasty for the Treatment of Distal Humerus Fractures.早期与延迟全肘关节置换治疗肱骨远端骨折的并发症比较。
J Hand Surg Am. 2024 Jul;49(7):707.e1-707.e7. doi: 10.1016/j.jhsa.2022.09.007. Epub 2023 Jan 27.
8
Intraarticular distal humerus fractures. Factors affecting functional outcome.
Clin Orthop Relat Res. 1996 Nov(332):200-8.
9
Ectopic ossification of the triceps muscle after application of bone morphogenetic protein-7 to the distal humerus for recalcitrant nonunion: a case report.
J Hand Surg Am. 2007 May-Jun;32(5):647-50. doi: 10.1016/j.jhsa.2007.03.001.
10
[Functional results of the parallel-plate technique for complex distal humerus fractures].[平行钢板技术治疗复杂肱骨远端骨折的功能结果]
Acta Orthop Traumatol Turc. 2009 Jan-Feb;43(1):21-7. doi: 10.3944/AOTT.2009.021.

引用本文的文献

1
Heterotopic ossification following severe radial head fractures: Clinical outcome and associated factors.严重桡骨头骨折后的异位骨化:临床结果及相关因素
Jt Dis Relat Surg. 2025 Jan 2;36(1):47-55. doi: 10.52312/jdrs.2025.1992. Epub 2024 Dec 18.
2
Distal humerus fractures: review of literature, tips, and tricks.肱骨远端骨折:文献综述、技巧与窍门
JSES Rev Rep Tech. 2023 Dec 18;4(3):639-646. doi: 10.1016/j.xrrt.2023.11.004. eCollection 2024 Aug.
3
Role of the NF-kB signalling pathway in heterotopic ossification: biological and therapeutic significance.
NF-κB 信号通路在异位骨化中的作用:生物学和治疗意义。
Cell Commun Signal. 2024 Mar 4;22(1):159. doi: 10.1186/s12964-024-01533-w.
4
Classification and Incidence of Heterotopic Ossifications in Relation to NSAID Prophylaxis after Elbow Trauma.肘部创伤后异位骨化的分类、发生率与非甾体抗炎药预防的关系
J Clin Med. 2024 Jan 24;13(3):667. doi: 10.3390/jcm13030667.
5
Heterotopic Ossification around the Elbow Revisited.肘部周围异位骨化再探讨。
Life (Basel). 2023 Dec 18;13(12):2358. doi: 10.3390/life13122358.
6
KLF2/PPARγ axis contributes to trauma-induced heterotopic ossification by regulating mitochondrial dysfunction.KLF2/PPARγ 轴通过调节线粒体功能障碍促进创伤性异位骨化。
Cell Prolif. 2024 Jan;57(1):e13521. doi: 10.1111/cpr.13521. Epub 2023 Jun 21.
7
Effectiveness and safety of a less-invasive MCL reconstruction technique for contracted or ossified ligaments in patients with elbow stiffness: An open-label, non-randomised, prospective, multicentre trial in China.一种用于肘关节僵硬患者挛缩或骨化韧带的微创内侧副韧带重建技术的有效性和安全性:一项在中国开展的开放标签、非随机、前瞻性、多中心试验。
EClinicalMedicine. 2022 Aug 12;52:101616. doi: 10.1016/j.eclinm.2022.101616. eCollection 2022 Oct.
8
Does posterior configuration have similar strength as parallel configuration for treating comminuted distal humerus fractures? A cadaveric biomechanical study.后向构型与平行构型治疗粉碎性肱骨远端骨折的强度是否相似?一项尸体生物力学研究。
BMC Musculoskelet Disord. 2021 May 14;22(1):440. doi: 10.1186/s12891-021-04302-9.
9
Risk Factors for the Occurrence and Progression of Posttraumatic Elbow Stiffness: A Case-Control Study of 688 Cases.创伤后肘关节僵硬发生及进展的危险因素:一项688例病例对照研究
Front Med (Lausanne). 2020 Dec 16;7:604056. doi: 10.3389/fmed.2020.604056. eCollection 2020.
10
ORIF of Distal Humerus Fractures with Modern Pre-contoured Implants is Still Associated with a High Rate of Complications.使用现代预塑形植入物治疗肱骨远端骨折的切开复位内固定术仍伴有较高的并发症发生率。
Indian J Orthop. 2020 Apr 24;54(5):570-579. doi: 10.1007/s43465-020-00124-4. eCollection 2020 Sep.