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严重桡骨头骨折后的异位骨化:临床结果及相关因素

Heterotopic ossification following severe radial head fractures: Clinical outcome and associated factors.

作者信息

Fischer Cornelius Sebastian, Porsche Johannes, Leyder Diane, Schüll Daniel, Histing Tina, Ziegler Patrick

机构信息

BG Unfallklinik Tübingen, Department of Traumatology and Reconstructive Surgery, Schnarrenbergstraße 95, 72076, Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.

出版信息

Jt Dis Relat Surg. 2025 Jan 2;36(1):47-55. doi: 10.52312/jdrs.2025.1992. Epub 2024 Dec 18.

Abstract

OBJECTIVES

This study aimed to evaluate clinical outcome, prevalence, severity, location, range of motion, and possible risk factors of heterotopic ossification (HO) following severe radial head fractures.

PATIENTS AND METHODS

In this retrospective study, 73 patients (40 males, 33 females; mean age: 51.4±15 years; range, 20 to 82 years) with Mason-Johnston type 3 and 4 radial head fractures were surgically treated with osteosynthesis or radial head arthroplasty (RHA) between September 2014 and February 2021. Fifty-one were examined in person, while 22 participated via questionnaire. The clinical outcome was assessed by the range of motion, the Disabilities of the Arm, Shoulder, and Hand questionnaire (DASH), and the 36-item Short-Form Health Survey (SF-36). Operative and postoperative details and the intake of HO prophylaxis were reviewed. Heterotopic ossification severity and location was evaluated on radiographs.

RESULTS

Heterotopic ossification was present in 52.1%, while in 31.5% of all participants, RHA was needed. Overall, 46.6% received additional ligamental refixation. The mean time to surgery was 8.9±11.9 days, and the mean DASH was 13.7±16.6. In patients treated with osteosynthesis, more HO was observed for Mason-Johnston type 4 injuries compared to Mason-Johnston type 3 injuries (p=0.028). Overall, more HO was present in Mason-Johnston type 4 injuries (63.6%) compared to Mason-Johnston type 3 injuries (42.5%), without reaching significance (p=0.072). No significant association between HO and time to surgery (p=0.716), implantation of RHA (p=0.127), or ligamental refixation (p=0.121) was detected. Regardless of intake of HO prophylaxis, nearly the same amount of HO (51.7% vs. 53.8%) was present. No differences between the HO and non-HO group were detected in the DASH (p=0.553) and the SF-36 (physical component, p=0.728; mental component, p=0.275).

CONCLUSION

Over 50% surgically treated radial head fractures classified as Mason-Johnston types 3 and 4 developed HO, while more severe injuries led to a higher prevalence of HO. No increased rates of HO were determined for delayed surgery, surgical treatment methods, and use of HO prophylaxis. Therefore, regular HO prophylaxis might not be needed. Additionally, no significant differences in functional scores and quality of life were detected between patients with and without HO.

摘要

目的

本研究旨在评估严重桡骨头骨折后异位骨化(HO)的临床结局、发生率、严重程度、位置、活动范围及可能的危险因素。

患者与方法

在这项回顾性研究中,2014年9月至2021年2月期间,73例(40例男性,33例女性;平均年龄:51.4±15岁;范围20至82岁)Mason-Johnston 3型和4型桡骨头骨折患者接受了手术内固定或桡骨头置换术(RHA)治疗。51例患者接受了亲自检查,22例通过问卷参与。通过活动范围、手臂、肩部和手部功能障碍问卷(DASH)以及36项简短健康调查(SF-36)评估临床结局。回顾了手术及术后细节以及HO预防措施的使用情况。通过X线片评估异位骨化的严重程度和位置。

结果

异位骨化发生率为52.1%,31.5%的患者需要进行RHA。总体而言,46.6%的患者接受了额外的韧带修复。手术平均时间为8.9±11.9天,平均DASH评分为13.7±16.6。与Mason-Johnston 3型损伤相比,Mason-Johnston 4型损伤采用内固定治疗的患者中观察到更多的HO(p=0.028)。总体而言,Mason-Johnston 4型损伤(63.6%)的HO发生率高于Mason-Johnston 3型损伤(42.5%),但差异无统计学意义(p=0.072)。未检测到HO与手术时间(p=0.716)、RHA植入(p=0.127)或韧带修复(p=0.121)之间存在显著关联。无论是否采取HO预防措施,HO的发生率几乎相同(51.7%对53.8%)。在DASH评分(p=0.553)和SF-36评分(身体部分,p=0.728;精神部分,p=0.275)方面,HO组与非HO组之间未检测到差异。

结论

超过50%接受手术治疗的Mason-Johnston 3型和4型桡骨头骨折患者发生了HO,损伤越严重,HO的发生率越高。延迟手术、手术治疗方法及HO预防措施的使用并未导致HO发生率增加。因此,可能不需要常规进行HO预防。此外,有HO和无HO的患者在功能评分和生活质量方面未检测到显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fee/11734851/0cec79482bce/JDRS-2025-36-1-047-055-F1.jpg

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