气泡的形成是由于环境温度和大气压力的变化而在胰岛素泵中发生的，但不是由于振动的结果。
Bubble formation occurs in insulin pumps in response to changes in ambient temperature and atmospheric pressure but not as a result of vibration.
机构信息
John Hunter Children's Hospital , Newcastle, New South Wales , Australia ; Mothers and Babies Research Group , Hunter Medical Research Institute , Newcastle, New South Wales , Australia ; University of Newcastle , Newcastle, New South Wales , Australia.
Gippsland Paediatric Diabetes Unit, Sale, Victoria , Australia.
出版信息
BMJ Open Diabetes Res Care. 2014 Aug 14;2(1):e000036. doi: 10.1136/bmjdrc-2014-000036. eCollection 2014.
INTRODUCTION
Bubble formation in insulin pump giving sets is a common problem. We studied change in temperature, change in atmospheric pressure, and vibration as potential mechanisms of bubble formation.
METHODS
5 Animas 2020 pumps with 2 mL cartridges and Inset II infusion systems, 5 Medtronic Paradigm pumps with 1.8 mL cartridge and Quickset and 3 Roche Accu-chek pumps with 3.15 mL cartridges were used. Temperature study: insulin pumps were exposed to a temperature change from 4°C to 37°C. Pressure study: insulin pumps were taken to an altitude of 300 m. Vibration study: insulin pumps were vigorously shaken. All were observed for bubble formation.
RESULTS
Bubble formation was observed with changes in temperature and atmospheric pressure. Bubble formation did not occur with vibration.
DISCUSSION
Changes in insulin temperature and atmospheric pressure are common and may result in bubble formation. Vibration may distribute bubbles but does not cause bubble formation.
引言
胰岛素泵输注装置中产生气泡是一个常见问题。我们研究了温度变化、大气压力变化和振动作为气泡形成的潜在机制。
方法
使用 5 个 Animas 2020 泵和 2 mL 药筒及 Inset II 输注系统、5 个 Medtronic Paradigm 泵和 1.8 mL 药筒及 Quickset、3 个 Roche Accu-chek 泵和 3.15 mL 药筒。温度研究：将胰岛素泵暴露在从 4°C 到 37°C 的温度变化中。压力研究：将胰岛素泵带到海拔 300 m 的高度。振动研究：剧烈摇晃胰岛素泵。所有这些都观察了气泡的形成。
结果
观察到温度和大气压力变化时会形成气泡。振动不会形成气泡，但会使气泡分散。
讨论
胰岛素温度和大气压力的变化很常见，可能导致气泡形成。振动可能会分散气泡，但不会导致气泡形成。
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