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可充电式与电池驱动式胰岛素泵的比较:温度波动

Comparison of rechargeable versus battery-operated insulin pumps: temperature fluctuations.

作者信息

Vereshchetin Paul, McCann Thomas W, Ojha Navdeep, Venugopalan Ramakrishna, Levy Brian L

机构信息

Johnson & Johnson Diabetes Care Companies, Chesterbrook, PA, USA.

出版信息

Med Devices (Auckl). 2016 Oct 14;9:371-376. doi: 10.2147/MDER.S116666. eCollection 2016.

Abstract

The role of continuous subcutaneous insulin infusion (insulin pumps) has become increasingly important in diabetes management, and many different types of these systems are currently available. This exploratory study focused on the reported heating issues that lithium-ion battery-powered pumps may have during charging compared with battery-operated pumps. It was found that pump temperature increased by 6.4°C during a long charging cycle of a lithiumion battery-operated pump under ambient temperatures. In an environmental-chamber kept at 35°C, the pump temperature increased by 4.4°C, which indicates that the pump temperature was above that of the recommended safety limit for insulin storage of 37°C. When designing new pumps, and when using currently available rechargeable pumps in warmer climates, the implications of these temperature increases should be taken into consideration. Future studies should also further examine insulin quality after charging.

摘要

持续皮下胰岛素输注(胰岛素泵)在糖尿病管理中的作用日益重要,目前有许多不同类型的此类系统可供使用。这项探索性研究关注的是锂离子电池供电的泵在充电过程中与电池驱动的泵相比可能出现的发热问题。研究发现,在环境温度下,锂离子电池驱动的泵进行长时间充电循环时,泵的温度升高了6.4°C。在保持在35°C的环境试验箱中,泵的温度升高了4.4°C,这表明泵的温度高于胰岛素储存推荐安全极限37°C。在设计新泵以及在气候较温暖的地区使用现有的可充电泵时,应考虑这些温度升高的影响。未来的研究还应进一步检查充电后的胰岛素质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90fb/5072507/481d0091bdcb/mder-9-371Fig1.jpg

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