Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Department of Chemical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
J Colloid Interface Sci. 2015 Jan 15;438:94-101. doi: 10.1016/j.jcis.2014.09.063. Epub 2014 Oct 2.
We report the synthesis of polyelectrolyte-decorated hybrid colloidal particles by using negatively charged polyelectrolyte complex (PEC) micelles as colloidal templates for silica mineralization under ambient conditions. The negatively charged polyelectrolytes including poly(acrylic acid) (PAA), poly(L-glutamic acid) (PLGA), and poly(styrene sulfonate) (PSS) were complexed with poly(L-lysine) at non-stoichiometric mixing weight percentage to form negatively charged PEC micelles. Varying the mixing weight percentage and molecular weight of polyelectrolytes led to the changes in the size and charge of the PEC particles. Silica mineralization in the complex core resulted in the colloidally stable hybrid particles decorated with different negatively charged polyelectrolytes. The colloidal properties of these polyelectrolyte-decorated hybrid particles were determined by the composition and decorated polyelectrolyte. This approach provided a simple and facile method to prepare polymer-decorated hybrid colloidal particles comprised of different polymers and their colloidal properties can be easily tuned by varying the decorated polymer and synthesis condition.
我们报告了通过使用带负电荷的聚电解质复合物（PEC）胶束作为胶体模板，在环境条件下进行硅烷化反应，合成聚电解质修饰的杂化胶体粒子。所使用的带负电荷的聚电解质包括聚丙烯酸（PAA）、聚 L-谷氨酸（PLGA）和聚苯乙烯磺酸钠（PSS），它们与聚 L-赖氨酸以非化学计量混合重量百分比复合，形成带负电荷的 PEC 胶束。改变聚电解质的混合重量百分比和分子量会导致 PEC 颗粒的尺寸和电荷发生变化。在复合物核内进行硅烷化反应，导致胶体稳定的杂化粒子被不同带负电荷的聚电解质修饰。这些带聚电解质修饰的杂化胶体粒子的胶体性质由组成和修饰的聚电解质决定。这种方法提供了一种简单易行的方法来制备由不同聚合物组成的聚合物修饰的杂化胶体粒子，并且可以通过改变修饰的聚合物和合成条件来轻松调节其胶体性质。
