Ayati S Bentolhoda, Bouazza-Marouf Kaddour, Kerr David
Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough LE11 3TU, United Kingdom.
Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough LE11 3TU, United Kingdom.
Med Eng Phys. 2015 Jan;37(1):34-41. doi: 10.1016/j.medengphy.2014.10.001. Epub 2014 Oct 30.
Electrical Impedance Tomography is a non-invasive and portable method that has good potential as an alternative to the conventional modalities for early detection of intracranial haematomas in high risk patients. Early diagnosis can reduce treatment delays and most significantly can impact patient outcomes. Two eight-electrode layouts, a standard ring full array (FA) and a semi-array (SA), were investigated for their ability to detect, localise and quantify simulated intracranial haematomas in vitro on ovine models for the purpose of early diagnosis. SA layout speeds up electrode application and avoids the need to move and lift the patient's head. Haematomas were simulated using gel samples with the same conductivity as blood. Both layouts, FA and SA, could detect the presence of haematomas at any location within the skull. The mean of the relative radial position error with respect to the brain radius was 7% for FA and 6% for SA, for haematomas close to the electrodes, and 11% for SA for haematomas far from the electrodes at the back of the head. Size estimation was not as good; the worst size estimation error for FA being around 30% while the best for SA was 50% for simulated haematomas close to the electrodes.
电阻抗断层成像(Electrical Impedance Tomography)是一种非侵入性的便携式方法,作为传统方法的替代方案,在早期检测高危患者颅内血肿方面具有良好潜力。早期诊断可以减少治疗延迟,并且对患者的治疗结果有显著影响。研究了两种八电极布局,即标准环形全阵列(FA)和半阵列(SA),在体外绵羊模型上检测、定位和量化模拟颅内血肿以进行早期诊断的能力。SA布局加快了电极应用速度,并且无需移动和抬起患者头部。使用与血液具有相同电导率的凝胶样本模拟血肿。FA和SA这两种布局都能够检测到头骨内任何位置的血肿。对于靠近电极的血肿,相对于脑半径的相对径向位置误差平均值,FA为7%,SA为6%;对于位于后脑勺远离电极的血肿,SA的误差为11%。尺寸估计效果不佳;对于靠近电极的模拟血肿,FA的最大尺寸估计误差约为30%,而SA的最佳误差为50%。