Basu Sandip, Kumar Rakesh, Ranade Rohit
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Jerbai Wadia Road, Parel, Mumbai 400012, India.
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
PET Clin. 2015 Jan;10(1):9-26. doi: 10.1016/j.cpet.2014.09.002. Epub 2014 Oct 14.
This article reviews the major treatment response evaluation guidelines in the domain of cancer imaging and how the potential of PET imaging, particularly with fluorodeoxyglucose, is increasingly explored in this important aspect of cancer management. Certain disease-specific response criteria (such as in lymphoma) are also reviewed with emphasis on the changes made over time and the main areas of concern in PET interpretation. The major present clinical applications are illustrated and potential new areas are discussed with regard to clinical applications in the future. Finally, the evolving role of newer and novel PET metrics, which hold promise in treatment response evaluation, is illustrated with examples.
本文回顾了癌症影像学领域主要的治疗反应评估指南，以及在癌症管理这一重要方面，正如何越来越多地探索正电子发射断层显像（PET）成像的潜力，尤其是使用氟脱氧葡萄糖的PET成像。还对某些特定疾病的反应标准（如淋巴瘤的反应标准）进行了回顾，重点是随着时间推移所做的改变以及PET解读中主要关注的领域。文中说明了目前主要的临床应用，并讨论了未来临床应用方面潜在的新领域。最后，通过实例说明了在治疗反应评估方面有望发挥作用的更新颖的PET指标不断演变的作用。
