Okubo Yoshiro, Seino Satoshi, Yabushita Noriko, Osuka Yosuke, Jung Songee, Nemoto Miyuki, Figueroa Rafael, Tanaka Kiyoji
Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan; The Japan Society for the Promotion of Science, 8 Ichiban, Chiyoda, Tokyo, 102-8472, Japan.
The Japan Society for the Promotion of Science, 8 Ichiban, Chiyoda, Tokyo, 102-8472, Japan; Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae, Itabashi, Tokyo, 173-0015, Japan.
Arch Gerontol Geriatr. 2015 Jan-Feb;60(1):45-51. doi: 10.1016/j.archger.2014.10.008. Epub 2014 Oct 22.
The purpose of this longitudinal study was to examine the association between habitual walking and multiple or injurious falls (falls) among community-dwelling older adults, by considering the relative risk of falling. A cohort of Japanese community-dwelling older adults (n=535) aged 60-91 years (73.1±6.6 year, 157 men and 378 women) who underwent community-based health check-ups from 2008 to 2012 were followed until 2013. Incidence rate of falls between walkers and non-walkers was compared separately by the number of risk factors (Groups R0, R1, R2, R3 and R4+). The Cox proportional hazard model was used to assess the association between habitual walking and falls separately by lower- (R<2) and higher- (R≥2) risk groups. In Groups R0 and R1, the incidence of falls was lower in walkers than non-walkers; however, in Groups R2, R3, and R4+, the incidence of falls was higher in walkers. The Cox proportional hazard model showed that habitual walking was not significantly associated with falls (hazard ratio (HR): 0.88, 95% confidence interval (CI): 0.48-1.62) among the lower risk group but that it was significantly associated with increased falls (HR: 1.89, 95% CI: 1.04-3.43) among the higher risk group. The significant interaction between habitual walking and higher risk of falling was found (P<0.05). When individuals have two or more risk factors for falling, caution is needed when recommending walking because walking can actually increase their risk of experiencing multiple or injurious falls.
这项纵向研究的目的是,通过考虑跌倒的相对风险,来考察社区居住的老年人习惯性步行与多次跌倒或伤害性跌倒(以下简称“跌倒”)之间的关联。对一组年龄在60 - 91岁(平均年龄73.1±6.6岁,男性157名,女性378名)、于2008年至2012年期间接受社区健康检查的日本社区居住老年人进行随访,直至2013年。按风险因素数量(R0、R1、R2、R3和R4+组)分别比较步行者和非步行者的跌倒发生率。采用Cox比例风险模型,分别按低风险组(R<2)和高风险组(R≥2)评估习惯性步行与跌倒之间的关联。在R0组和R1组中,步行者的跌倒发生率低于非步行者;然而,在R2、R3和R4+组中,步行者的跌倒发生率更高。Cox比例风险模型显示,在低风险组中,习惯性步行与跌倒无显著关联(风险比(HR):0.88,95%置信区间(CI):0.48 - 1.62),但在高风险组中,习惯性步行与跌倒增加显著相关(HR:1.89,95% CI:1.04 - 3.43)。发现习惯性步行与较高跌倒风险之间存在显著交互作用(P<0.05)。当个体有两个或更多跌倒风险因素时,推荐步行时需谨慎,因为步行实际上可能增加其经历多次跌倒或伤害性跌倒的风险。