Vandenbos F, Figueredo M, Tarhini A, Ribière J
Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France; Centre de soins de suite et de rééducation « La Maison du Mineur », 577, avenue Henri-Giraud, 06141 Vence, France.
Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France.
Rev Pneumol Clin. 2015 Feb;71(1):57-9. doi: 10.1016/j.pneumo.2014.09.002. Epub 2014 Nov 20.
Leflunomide is an immunosuppressant drug used in rheumatoid arthritis and psoriatic arthritis. This product may cause rare but serious interstitial lung disease that appear at the beginning of treatment. This is why leflunomide should be prescribed and monitored in hospital. We present the case of a 71 years old woman who presented a pleuro-pericarditis with an increase of CA 125 during a treatment with leflunomide. This is the second case reported in the literature. The outcome was favorable after discontinuation of leflunomide.
来氟米特是一种用于治疗类风湿性关节炎和银屑病关节炎的免疫抑制剂药物。该产品可能会导致罕见但严重的间质性肺病，且在治疗开始时出现。这就是为什么来氟米特应在医院开具处方并进行监测。我们报告了一例71岁女性在使用来氟米特治疗期间出现胸膜心包炎并伴有CA 125升高的病例。这是文献中报道的第二例。停用米氟米特后病情转好。
