Pitossi Fernando J, Podhajcer Osvaldo L
1 Laboratorie of Regenerative and Protective Therapies of the Central Nervous System, Fundación Instituto Leloir-IIBBA CONICET , Buenos Aires, Argentina .
Stem Cells Dev. 2014 Dec;23 Suppl 1:17-9. doi: 10.1089/scd.2014.0403.
Since Takahashi and Yamanaka demonstrated for the first time that fully differentiated somatic cells can be reprogrammed to a pluripotent state with a small group of transcription factors a revolution erupted in the regenerative medicine field. New advances showing direct differentiation of mature cells increased the excitement of the field. This work describes the present situation of the field in Argentina and the efforts implemented by science authorities to strengthen and push the field forward.
自从高桥和山中首次证明完全分化的体细胞可以通过一小群转录因子重编程为多能状态以来,再生医学领域爆发了一场革命。新的进展表明成熟细胞可以直接分化,这增加了该领域的热度。这项工作描述了阿根廷该领域的现状以及科学当局为加强和推动该领域发展所做的努力。