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Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction.

作者信息

Lin Chia-Hsien, Chen Jung-Kuei, Ko Tai-Ming, Wei Chun-Yu, Wu Jer-Yuarn, Chung Wen-Hung, Chen Shih-Yang, Liao You-Di, Hung Shuen-Iu, Chen Yuan-Tsong

机构信息

Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

出版信息

J Allergy Clin Immunol. 2015 Apr;135(4):1063-1065.e5. doi: 10.1016/j.jaci.2014.09.041. Epub 2014 Nov 11.

DOI:10.1016/j.jaci.2014.09.041
PMID:25458913
Abstract
摘要

相似文献

1
Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction.别嘌醇诱导的严重皮肤不良反应的免疫学基础：HLA - B*58:01限制的药物特异性T细胞激活及分子相互作用
J Allergy Clin Immunol. 2015 Apr;135(4):1063-1065.e5. doi: 10.1016/j.jaci.2014.09.041. Epub 2014 Nov 11.
2
Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response.别嘌醇超敏反应主要由剂量依赖性的氧嘌呤醇特异性 T 细胞反应介导。
Clin Exp Allergy. 2013 Nov;43(11):1246-55. doi: 10.1111/cea.12184.
3
Analysis of HLA-B Allelic Variation and IFN-γ ELISpot Responses in Patients with Severe Cutaneous Adverse Reactions Associated with Drugs.药物相关性严重皮肤不良反应患者 HLA-B 等位基因变异与 IFN-γ ELISpot 反应分析
J Allergy Clin Immunol Pract. 2019 Jan;7(1):219-227.e4. doi: 10.1016/j.jaip.2018.05.004. Epub 2018 May 22.
4
Oxypurinol directly and immediately activates the drug-specific T cells via the preferential use of HLA-B*58:01.别嘌醇醇通过优先使用 HLA-B*58:01 直接且即刻激活药物特异性 T 细胞。
J Immunol. 2014 Apr 1;192(7):2984-93. doi: 10.4049/jimmunol.1302306. Epub 2014 Mar 3.
5
Pharmacogenetics of allopurinol--making an old drug safer.别嘌醇的药物遗传学——让老药更安全。
J Clin Pharmacol. 2013 Jul;53(7):675-9. doi: 10.1002/jcph.67. Epub 2013 Feb 4.
6
Genotyping HLA-B*5801 for Allopurinol-Induced Severe Cutaneous Adverse Reactions: An Accurate and Prompt Method.通过基因分型HLA - B*5801预测别嘌醇诱导的严重皮肤不良反应：一种准确且快速的方法。
Clin Transl Sci. 2015 Dec;8(6):834-6. doi: 10.1111/cts.12365. Epub 2015 Dec 14.
7
[The associations between idiosyncratic adverse drug reactions and HLA alleles and their underlying mechanism].[特异质药物不良反应与人类白细胞抗原等位基因的关联及其潜在机制]
Yao Xue Xue Bao. 2013 Jun;48(6):799-808.
8
Allopurinol-induced severe cutaneous adverse reactions.别嘌醇诱发的严重皮肤不良反应。
Ann Rheum Dis. 2016 Apr;75(4):e20. doi: 10.1136/annrheumdis-2015-209108. Epub 2016 Jan 19.
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Detection of HLA-B*58:01 with TaqMan assay and its association with allopurinol-induced sCADR.采用 TaqMan assay 检测 HLA-B*58:01 及其与别嘌醇诱导的 sCADR 的关系。
Clin Chem Lab Med. 2015 Feb;53(3):383-90. doi: 10.1515/cclm-2014-0251.
10
Impact of the HLA-B(*)58:01 Allele and Renal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions.HLA - B(*)58:01等位基因及肾功能损害对别嘌醇诱导的皮肤不良反应的影响
J Invest Dermatol. 2016 Jul;136(7):1373-1381. doi: 10.1016/j.jid.2016.02.808. Epub 2016 Mar 18.

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HLA-B*58:01 genotyping prevalence and the association with allopurinol-induced severe cutaneous adverse reactions: a living systematic review and meta-analysis.HLA - B*58:01基因分型患病率及其与别嘌醇诱导的严重皮肤不良反应的关联：一项实时系统评价和荟萃分析。
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2
TSC22 domain family member 3 links natural killer cells to CD8+ T cell-mediated drug hypersensitivity.TSC22结构域家族成员3将自然杀伤细胞与CD8 + T细胞介导的药物超敏反应联系起来。
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Viral reactivation and clinical outcomes in Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS).
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Severe cutaneous adverse reactions.严重皮肤不良反应。
Nat Rev Dis Primers. 2024 Apr 25;10(1):30. doi: 10.1038/s41572-024-00514-0.
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The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors.别嘌醇代谢物，氧嘌呤醇，可驱动缓解的过敏反应病例和无用药史的健康供体中药物反应性 T 细胞的寡克隆扩增。
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Systemic Versus Topical Corticosteroids in the Treatment of DRESS: A Retrospective Cohort Study Followed by a Meta-Analysis.全身性皮质类固醇与局部皮质类固醇治疗 DRESS：一项回顾性队列研究及荟萃分析。
Am J Clin Dermatol. 2023 Jul;24(4):637-647. doi: 10.1007/s40257-023-00776-6. Epub 2023 May 3.
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Biomedicines. 2023 Jan 10;11(1):177. doi: 10.3390/biomedicines11010177.
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Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity.药物性超敏反应中导致氨苯砜诱导的 HLA-B*13:01 介导的特异性 T 细胞反应的功能和结构特征。
J Biomed Sci. 2022 Aug 13;29(1):58. doi: 10.1186/s12929-022-00845-8.
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