Yamakama H, Baba M, Shiba M, Urabe N, Fujisawa T, Yamaguchi Y, Oiwa T
Nihon Kyobu Shikkan Gakkai Zasshi. 1989 Jan;27(1):64-70.
In order to improve the preoperative diagnostic rate of lung cancer, histological examination was performed by transbronchial brushing in 35 cases, and diagnostic contribution of brushing specimen was compared with that of transbronchial forceps biopsy (TBFB). Histological structures were well preserved in the histology section of brushing specimens, especially in cases of small cell lung cancer. The positive rate of brushing histology was 46%, which was the same as that of TBFB. The total histological diagnostic rate was 66% with simultaneous examination of bronchial brushing and TBFB specimens. Consequently, the use of brushing specimens for histologic evaluation made an additional contribution to the correct positive histology diagnostic rate. Brushing histology is indicated for all types of lung cancer, because in most TBFB-negative cases, biopsies were performed from inappropriate sites of tumors or their materials wer crushed by forceps. It was suggested that concomitant application of brushing specimen for histology examination, contributed to more accurate preoperative histology diagnosis for lung cancer.
为提高肺癌术前诊断率，对35例患者行经支气管刷检进行组织学检查，并将刷检标本的诊断价值与经支气管钳取活检（TBFB）进行比较。刷检标本的组织学切片中组织结构保存良好，尤其是小细胞肺癌病例。刷检组织学阳性率为46%，与TBFB相同。支气管刷检和TBFB标本同时检查时，总组织学诊断率为66%。因此，使用刷检标本进行组织学评估对正确的组织学阳性诊断率有额外贡献。刷检组织学适用于所有类型的肺癌，因为在大多数TBFB阴性病例中，活检取材部位不当或组织被钳子挤压。建议同时应用刷检标本进行组织学检查，有助于更准确地进行肺癌术前组织学诊断。
