Pakeerappa Praveen N, Birthi Pravardhan, Salles Sara
Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY(∗).
Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY(†).
PM R. 2015 Mar;7(3):326-8. doi: 10.1016/j.pmrj.2014.10.013. Epub 2014 Nov 6.
Stiff person syndrome (SPS) is a rare neurologic disorder of unknown etiology characterized by increased resting muscle tone, progressive rigidity, and stiffness of the axial musculature. We present a case of a 48-year-old male patient with SPS who experienced facial and neck muscle spasms that were uncontrolled with oral medications and the use of an intrathecal baclofen pump. Botulinum toxin A injections into the bilateral masseter and neck paraspinal muscles provided pain relief and spasm control, illustrating the use of botulinum toxin A injections in the small muscles of face and neck in patients with SPS.
僵人综合征（SPS）是一种病因不明的罕见神经系统疾病，其特征为静息肌张力增加、进行性僵硬以及轴性肌肉僵硬。我们报告一例48岁男性SPS患者，该患者出现面部和颈部肌肉痉挛，口服药物及使用鞘内注射巴氯芬泵均无法控制。向双侧咬肌和颈部椎旁肌注射A型肉毒毒素可缓解疼痛并控制痉挛，这说明了A型肉毒毒素注射在SPS患者面部和颈部小肌肉中的应用。
