Tanaka Y, Kakizoe T, Tobisu K, Takai K
Nihon Hinyokika Gakkai Zasshi. 1989 Feb;80(2):229-35. doi: 10.5980/jpnjurol1989.80.229.
We presented 3 cases of renal cell carcinoma with hepatic lesion, for which it was difficult to make a diagnosis preoperatively. The hepatic lesion was cavernous hemangioma of the liver, liver metastasis of renal cell carcinoma or hepatocellular carcinoma. To discuss the strategy of treatment for liver metastasis of renal cell carcinoma at the time of nephrectomy, or in the follow-up period after nephrectomy, we reviewed the 188 cases of renal cell carcinoma which were nephrectomized from December, 1962 to June, 1988. At the time of nephrectomy, there was only 1 case that had concurrent liver metastasis. In 4 cases, liver metastasis was found at autopsy, and in 15 cases, in the follow-up period after nephrectomy. We analysed these 15 cases and classified them into 2 groups. One was "early metastasis group", i.e., liver metastasis was found within 18 months after nephrectomy, and the other was "late metastasis group", i.e., liver metastasis detected more than 6 years after nephrectomy. In the "early metastasis group", 2 lived 10 months or 57 months, but 5 died within 1 month after the appearance of liver metastasis. In the "late metastasis group", 4 of 7 lived more than 2 years after the appearance of liver metastasis and the median survival was 21 months. In both groups, when liver metastasis was found, there were metastases in multiple organs and the hepatic lesions were multiple.(ABSTRACT TRUNCATED AT 250 WORDS)
我们报告了3例伴有肝脏病变的肾细胞癌病例，术前很难做出诊断。肝脏病变为肝海绵状血管瘤、肾细胞癌肝转移或肝细胞癌。为了探讨肾切除术时或肾切除术后随访期间肾细胞癌肝转移的治疗策略，我们回顾了1962年12月至1988年6月期间接受肾切除术的188例肾细胞癌病例。肾切除时，仅有1例同时伴有肝转移。4例在尸检时发现肝转移，15例在肾切除术后随访期间发现肝转移。我们对这15例病例进行了分析并将其分为2组。一组为“早期转移组”，即肾切除术后18个月内发现肝转移；另一组为“晚期转移组”，即肾切除术后6年以上发现肝转移。在“早期转移组”中，2例分别存活了10个月或57个月，但5例在肝转移出现后1个月内死亡。在“晚期转移组”中，7例中有4例在肝转移出现后存活超过2年，中位生存期为21个月。在两组中，当发现肝转移时，均有多个器官转移且肝脏病变为多发。（摘要截短至250字）
