Sudhaus Sigrid, Held Sabine, Schoofs Daniela, Bültmann Janina, Dück Irina, Wolf Oliver T, Hasenbring Monika I
Department of Medical Psychology and Medical Sociology, Faculty of Medicine, Ruhr-University of Bochum, 44780 Bochum, Germany.
Department of Cognitive Psychology, Faculty of Psychology, Ruhr-University of Bochum, 44780 Bochum, Germany; Clinic for Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30625 Hannover, Germany.
Psychoneuroendocrinology. 2015 Feb;52:195-9. doi: 10.1016/j.psyneuen.2014.11.011. Epub 2014 Nov 20.
Recent clinical studies in patients with lower back pain indicate that maladaptive fear-avoidance- and endurance-related pain responses (FAR and ER) have an influence on pain-induced physiological stress levels. The aim of the present study was to follow-up these results under well-controlled laboratory conditions. For this purpose, 30 healthy adults were asked to indicate their usual responses to pain, and were then confronted with an experimental pain stimulus (cold pressor test). Cortisol served as a measure of physiological stress. The results reveal positive associations between cortisol and FAR patterns, and negative associations between cortisol and behavioral ER. Conceivably, FAR contribute to long-lasting elevated stress levels in patients with stress-related musculoskeletal pain. In contrast, short-term, stress-lowering effects of ER might even be considered an advantage in coping with pain.
近期针对下背部疼痛患者的临床研究表明，适应不良的恐惧回避和耐力相关疼痛反应（FAR和ER）会对疼痛引起的生理应激水平产生影响。本研究的目的是在严格控制的实验室条件下追踪这些结果。为此，30名健康成年人被要求表明他们对疼痛的通常反应，然后面对实验性疼痛刺激（冷加压试验）。皮质醇用作生理应激的指标。结果显示皮质醇与FAR模式之间呈正相关，皮质醇与行为性ER之间呈负相关。可以想象，FAR会导致与压力相关的肌肉骨骼疼痛患者的应激水平长期升高。相比之下，ER的短期减压作用甚至可能被视为应对疼痛的一个优势。
