苯腙（一种单纯疱疹病毒糖基化抑制剂）作用机制的一些理论方面
Some theoretical aspects of the mechanism of action of benzhydrazone, an inhibitor of glycosylation in herpes simplex virus.
作者信息
Paganetto G, Palù G, Tognon M
机构信息
Institute of Biological Sciences, School of Medicine, University of Verona, Italy.
出版信息
Microbiologica. 1989 Apr;12(2):121-7.
PMID:2546019
Abstract
Some hypotheses of the mechanism of action of benzhydrazone, a selective inhibitor of herpes simplex virus glycoprotein biosynthesis, are presented in this paper. Comparative analysis of different models indicates that the drug may interfere with herpes simplex virus DNA. Thus, benzhydrazone seems to act like a bifunctional alkylating agent.
摘要
本文提出了苯腙（一种单纯疱疹病毒糖蛋白生物合成的选择性抑制剂）作用机制的一些假说。不同模型的比较分析表明，该药物可能会干扰单纯疱疹病毒的DNA。因此，苯腙似乎起到了双功能烷基化剂的作用。
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