与玻璃体内注射奥克纤溶酶相关的严重急性视力丧失、色觉障碍以及频域光学相干断层扫描上椭圆体带的变化。
Severe acute vision loss, dyschromatopsia, and changes in the ellipsoid zone on sd-oct associated with intravitreal ocriplasmin injection.
作者信息
Quezada Ruiz Carlos, Pieramici Dante J, Nasir Maʼan, Rabena Melvin, Avery Robert L
机构信息
California Retina Consultants and Research Foundation, Santa Barbara, California.
出版信息
Retin Cases Brief Rep. 2015 Spring;9(2):145-8. doi: 10.1097/ICB.0000000000000120.
PURPOSE
To present the long-term follow-up of a patient injected with intravitreal ocriplasmin who experienced severe acute post-intravitreal ocriplasmin complications.
METHODS
Case report.
RESULTS
A 68-year-old man with vitreomacular traction was treated with intravitreal ocriplasmin. He experienced dyschromatopsia, severe acute visual acuity, and field loss 4 hours after the injection. This was accompanied by decreased reflectivity on spectral domain optical coherence tomography in the ellipsoid zone of the outer retina. These changes were transient, and 3 years after the injection, the patient is asymptomatic and no outer reflectivity changes are noted on his spectral domain optical coherence tomography images.
CONCLUSION
Acute visual changes and spectral domain optical coherence tomography hyporeflectivity in the ellipsoid zone after intravitreal ocriplasmin can occur in some individuals, but in this case, these changes were reversible, and there have been no long-term implications.
目的
报告1例玻璃体内注射奥克纤溶酶后出现严重急性并发症患者的长期随访情况。
方法
病例报告。
结果
1例68岁患有玻璃体黄斑牵拉的男性接受了玻璃体内奥克纤溶酶治疗。注射后4小时，他出现了色觉异常、严重急性视力下降和视野缺损。同时，视网膜外层椭圆体带在光谱域光学相干断层扫描上的反射率降低。这些变化是短暂的，注射3年后，患者无症状，光谱域光学相干断层扫描图像上未发现外层反射率变化。
结论
玻璃体内注射奥克纤溶酶后，部分个体可能出现急性视力变化和椭圆体带光谱域光学相干断层扫描低反射率，但在本病例中，这些变化是可逆的，且无长期影响。
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