Dylewski J, Wiesenfeld H, Latour A
Department of Medicine and Radiology, St. Mary's Medical Center, Montreal, Quebec, Canada.
Rev Infect Dis. 1989 May-Jun;11(3):470-3. doi: 10.1093/clinids/11.3.470.
Clostridium perfringens is commonly present in the female genital tract. Uterine infection with this organism is a potentially fatal disease infrequently seen in obstetric practice. The manifestations of C. perfringens uterine infection are variable, ranging from endometritis to gas gangrene with fulminant septicemia. The usual precipitating event has been septic abortion, but such infections can also occur spontaneously in uterine tumors and after complicated deliveries requiring mechanical intervention. Diagnosis may be aided by radiologic techniques, and treatment involves high-dose penicillin and possibly surgery. We report two cases and review the clinical presentation and the diagnostic and therapeutic aspects of this disease.
产气荚膜梭菌通常存在于女性生殖道中。由该微生物引起的子宫感染是一种潜在的致命疾病，在产科实践中很少见。产气荚膜梭菌子宫感染的表现各不相同，从子宫内膜炎到伴有暴发性败血症的气性坏疽。常见的诱发因素是感染性流产，但此类感染也可能自发发生于子宫肿瘤以及需要机械干预的复杂分娩后。放射学技术可能有助于诊断，治疗包括大剂量青霉素治疗，可能还需要手术。我们报告两例病例，并对该疾病的临床表现、诊断和治疗方面进行综述。
