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[Syncytia formation in cultures and analysis of the protein composition of various strains of caprine arthritis encephalitis virus (CAEV)].

作者信息

Blondin I, Grillet C, Thiogane Y

机构信息

Laboratoire de recherches sur la Pathologie des Petits Ruminants, INRA, Ecole Nationale Vétérinaire de Lyon, Charbonnières, France.

出版信息

Ann Rech Vet. 1989;20(2):153-8.

PMID:2546478
Abstract

The syncytia forming activity of 9 caprine arthritis encephalitis virus (CAEV) strains isolated from lesions or normal goat tissue was evaluated in vitro. No discrepancies were seen between the structural proteins of the 9 strains by gel electrophoresis. Goat synovial membrane cells were the most susceptible to the 9 CAEV strains. Goat monocytes in culture were susceptible to all the strains tested. At 39 degrees C, all the strains produced more syncitial lesions. In nasal turbinate cells, 2 strains did not form syncytia; one strain induced lysis of all the goat cells used.

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