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慢性阻塞性肺疾病的远程医疗保健:关于身体状况和呼吸困难的系统评价与荟萃分析

Telehealthcare in COPD: a systematic review and meta-analysis on physical outcomes and dyspnea.

作者信息

Lundell Sara, Holmner Åsa, Rehn Börje, Nyberg Andre, Wadell Karin

机构信息

Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, S-90187 Umeå, Sweden.

Department of Radiation Sciences, Umeå University, S-90187 Umeå, Sweden.

出版信息

Respir Med. 2015 Jan;109(1):11-26. doi: 10.1016/j.rmed.2014.10.008. Epub 2014 Oct 27.

Abstract

BACKGROUND

Only a minority of patients with chronic obstructive pulmonary disease (COPD) have access to pulmonary rehabilitation (PR). Home-based solutions such as telehealthcare, have been used in efforts to make PR more available. The aim of this systematic review was to investigate the effects of telehealthcare on physical activity level, physical capacity and dyspnea in patients with COPD, and to describe the interventions used.

METHODS

Randomized controlled trials were identified through database searches, reference lists and included authors. Articles were reviewed based on eligibility criteria by three authors. Risk of bias was assessed by two authors. Standardized mean differences (SMD) or mean differences (MD) with 95% CI were calculated. Forest plots were used to present data visually.

RESULTS

Nine studies (982 patients) were included. For physical activity level, there was a significant effect favoring telehealthcare (MD, 64.7 min; 95% CI, 54.4-74.9). No difference between groups was found for physical capacity (MD, -1.3 m; 95% CI, -8.1-5.5) and dyspnea (SMD, 0.088; 95% CI, -0.056-0.233). Telehealthcare was promoted through phone calls, websites or mobile phones, often combined with education and/or exercise training. Comparators were ordinary care, exercise training and/or education.

CONCLUSIONS

The use of telehealthcare may lead to improvements in physical activity level, although the results should be interpreted with caution given the heterogeneity in studies. This is an important area of research and further studies of the effect of telehealthcare for patients with COPD would be beneficial.

REGISTRATION

In PROSPERO 2012: CRD42012003294.

STUDY PROTOCOL

http://www.crd.york.ac.uk/PROSPEROFILES/3294_PROTOCOL_20121016.pdf.

摘要

背景

只有少数慢性阻塞性肺疾病(COPD)患者能够接受肺康复治疗(PR)。诸如远程医疗保健等基于家庭的解决方案已被用于努力使肺康复治疗更易获得。本系统评价的目的是研究远程医疗保健对COPD患者身体活动水平、身体能力和呼吸困难的影响,并描述所采用的干预措施。

方法

通过数据库检索、参考文献列表和纳入作者来识别随机对照试验。由三位作者根据纳入标准对文章进行评审。由两位作者评估偏倚风险。计算标准化均数差(SMD)或均数差(MD)及95%置信区间(CI)。采用森林图直观呈现数据。

结果

纳入9项研究(982例患者)。对于身体活动水平,远程医疗保健有显著效果(MD,64.7分钟;95%CI,54.4 - 74.9)。身体能力(MD,-1.3米;95%CI,-8.1 - 5.5)和呼吸困难(SMD,0.088;95%CI,-0.056 - 0.233)方面未发现组间差异。远程医疗保健通过电话、网站或手机进行推广,通常与教育和/或运动训练相结合。对照措施为常规护理、运动训练和/或教育。

结论

尽管鉴于研究的异质性,结果应谨慎解读,但使用远程医疗保健可能会改善身体活动水平。这是一个重要的研究领域,进一步研究远程医疗保健对COPD患者的影响将是有益的。

注册情况

在PROSPERO 2012中注册:CRD42012003294。

研究方案

http://www.crd.york.ac.uk/PROSPEROFILES/3294_PROTOCOL_20121016.pdf。

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