Jang Min-Seok, Kim Hyo Yeol, Dhong Hun-Jong, Chung Seung-Kyu, Hong Sang Duk, Cho Hyun-Jin
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
J Plast Reconstr Aesthet Surg. 2015 Mar;68(3):344-50. doi: 10.1016/j.bjps.2014.10.037. Epub 2014 Oct 30.
The understanding of facial fat volume change with aging is essential for facial rejuvenation. The aim of this study was to investigate aging-related alterations of midfacial fat thickness (FT) using computed tomographic images.
Eighty computed tomographic scans of patients of four age groups (20s, 40s, 60s, and 80s), who underwent septoturbinoplasty, were studied. The body mass index of the patients was limited to 25.0±2 kg/m2. At seven consistent points in the midface including the infraorbital (two points), mid-cheek (two) and nasojugal area (three), the measurements of the total facial thickness (TFT) and FT were conducted on a reconstructed sagittal plane by four trained observers using a medical imaging software.
The interrater reliabilities for each measured point were excellent (overall intraclass correlation coefficients=0.94). There was no significant difference in the TFTs of each point among the age groups (all P>0.05). By contrast, the FTs of the four points (infraorbital and nasojugal area) showed a significant increment in the elderly than in young subjects (all P<0.011). The FTs of the mid-cheek exhibited almost no change among the age groups (all P>0.05).
This study suggests that the midfacial fat pad is thickened in the elderly and that there is a site specificity in the alteration.
了解面部脂肪体积随年龄的变化对于面部年轻化至关重要。本研究的目的是使用计算机断层扫描图像研究面中部脂肪厚度（FT）与衰老相关的变化。
对接受鼻中隔鼻甲成形术的四个年龄组（20多岁、40多岁、60多岁和80多岁）的80例患者的计算机断层扫描进行研究。患者的体重指数限制在25.0±2kg/m²。在面中部七个一致的点，包括眶下（两个点）、面颊中部（两个点）和鼻颧区（三个点），由四名训练有素的观察者使用医学成像软件在重建的矢状面上测量总面部厚度（TFT）和FT。
每个测量点的观察者间可靠性极佳（总体组内相关系数=0.94）。各年龄组间各点的TFT无显著差异（所有P>0.05）。相比之下，四个点（眶下和鼻颧区）的FT在老年人中比年轻受试者显著增加（所有P<0.011）。面颊中部的FT在各年龄组间几乎没有变化（所有P>0.05）。
本研究表明，老年人面中部脂肪垫增厚，且这种变化具有部位特异性。
