Section of Otolaryngology, Department of Surgery, Yale School of Medicine, 800 Howard Avenue, 4th Floor, ENT Office, New Haven, CT, USA.
Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Aesthetic Plast Surg. 2018 Aug;42(4):995-1001. doi: 10.1007/s00266-018-1134-x. Epub 2018 Apr 11.
Volumetric changes to facial fat that occur with aging remain poorly understood. The aim of this study was to evaluate for longitudinal changes to midfacial fat volumes in a group of individuals.
We conducted a retrospective longitudinal study of adult subjects who underwent multiple facial computed tomographic (CT) scans timed at least 8 years apart. Subjects who underwent facial surgery or suffered facial trauma were excluded. Facial CT scans were analyzed, and superficial cheek fat volumes were measured and compared to track changes that occurred with aging.
Fourteen subjects were included in our analysis of facial aging (5 male, 9 female; mean initial age 50.9 years; mean final age 60.4 years). In the right superficial cheek there was an increase in mean (SD) superficial fat volume from 10.33 (2.01) to 10.50 (1.80) cc, which was not statistically significant (P = 0.75). Similar results were observed in the left cheek. There were no statistically significant longitudinal changes to caudal, middle, or cephalad subdivisions of bilateral superficial cheek fat. A simple linear regression was performed to predict superficial cheek fat pad volume based on age which did not reach statistical significance (P = 0.31), with an R of 0.039.
This study is the first to quantitatively assess for longitudinal changes to midfacial fat in a group of individuals. Superficial cheek fat remained stable as subjects aged from approximately 50 to 60 years old, with no change in total volume or redistribution within a radiographically defined compartment.
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随着年龄的增长，面部脂肪的容积变化仍知之甚少。本研究旨在评估一组个体的中面部脂肪体积的纵向变化。
我们对至少相隔 8 年接受多次面部计算机断层扫描（CT）的成年受试者进行了回顾性纵向研究。排除接受面部手术或遭受面部创伤的受试者。分析面部 CT 扫描，并测量浅层颊脂体积以追踪与衰老相关的变化。
我们对面部老化的 14 名受试者（5 名男性，9 名女性；平均初始年龄 50.9 岁；平均最终年龄 60.4 岁）进行了分析。右侧浅层颊脂在平均（SD）浅层脂肪体积从 10.33（2.01）增加到 10.50（1.80）cc，但无统计学意义（P=0.75）。左侧颊脂也观察到类似的结果。双侧浅层颊脂的尾侧、中部和头侧亚区均无统计学意义的纵向变化。对基于年龄的浅层颊脂垫体积进行简单线性回归，未达到统计学意义（P=0.31），R 为 0.039。
本研究首次定量评估了一组个体的中面部脂肪的纵向变化。浅层颊脂在 50 岁至 60 岁左右的受试者中保持稳定，总容积无变化，在影像学定义的隔室内无重新分布。
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