表现为甲状腺功能减退性甲状腺肿的朗格汉斯细胞组织细胞增多症：一种独特的表现。
Langerhans cell histiocytosis presenting as hypothyroid goitre: a unique presentation.
作者信息
Marupudi Krishna Chaitanya, Karanth Suman S, Thomas Joseph
机构信息
Department of Internal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Department of Medical Oncology, Kasturba Medical College, Manipal, Karnataka, India.
出版信息
BMJ Case Rep. 2014 Dec 2;2014:bcr2014206760. doi: 10.1136/bcr-2014-206760.
Abstract
Langerhans cell histiocytosis (LCH) is a disease involving the antigen presenting cells, which can range from a single system involvement with an indolent course to a multisystem disease with increased morbidity. We present a rare case of LCH presenting as hypothyroid goitre that was successfully treated as per the LCH III trial protocol with a combination of vinblastine and oral prednisolone. We highlight the need for awareness of this rare presentation of LCH as a painless goitre which is often misdiagnosed as poorly differentiated thyroid carcinoma or overlooked as a benign disease.
摘要
朗格汉斯细胞组织细胞增多症（LCH）是一种涉及抗原呈递细胞的疾病，其病情范围可从单一系统受累且病程缓慢到多系统疾病且发病率增加。我们报告了一例罕见的LCH病例，表现为甲状腺功能减退性甲状腺肿，按照LCH III试验方案，采用长春碱和口服泼尼松龙联合治疗，取得了成功。我们强调，需要认识到LCH这种罕见的表现形式，即无痛性甲状腺肿，它常常被误诊为低分化甲状腺癌或被当作良性疾病而被忽视。
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