Case Western Reserve University School of Medicine; Case Comprehensive Cancer Center; Cleveland Clinic Foundation; and University Hospitals of Cleveland, Cleveland, OH
Case Western Reserve University School of Medicine; Case Comprehensive Cancer Center; Cleveland Clinic Foundation; and University Hospitals of Cleveland, Cleveland, OH.
J Oncol Pract. 2015 Jan;11(1):e50-8. doi: 10.1200/JOP.2014.000034. Epub 2014 Dec 2.
There is a dearth of studies on cancer outcomes in individuals with mental illness. We compared breast cancer outcomes in Medicaid beneficiaries with and without mental illness.
Using records from the 1996 to 2005 Ohio Cancer Incidence Surveillance System (OCISS) and Medicaid files, we identified fee-for-service women age < 65 years diagnosed with incident invasive breast cancer who had enrolled in Medicaid ≥ 3 months before cancer diagnosis (n = 2,177). We retrieved cancer stage, patient demographics, and county of residence from the OCISS. From Medicaid claims data, we identified breast cancer treatment based on procedure codes and mental illness status based on diagnosis codes, prescription drugs dispensed, and service codes. We developed logistic regression models to examine the association between mental illness, cancer stage, and treatment for locoregional disease, adjusting for potential confounders.
Women with mental illness represented 60.2% of the study population. Adjusting for potential confounders, women with mental illness were less likely than those without mental illness to have unstaged or unknown-stage cancer (adjusted odds ratio [OR], 0.61; 95% CI, 0.44 to 0.86; P = .005) or to be diagnosed with distant-stage cancer (adjusted OR, 0.59; 95% CI, 0.40 to 0.85; P = .005). We observed no difference by mental illness status in receipt of definitive treatment (adjusted OR, 1.04; 95% CI, 0.84 to 1.29; P = .08).
Among Ohio Medicaid beneficiaries, women with mental illness did not experience disparities in breast cancer stage or treatment of locoregional disease. These findings may reflect the equalizing effects of Medicaid through vulnerable individuals' improved access to both physical and mental health care.
精神疾病患者的癌症结局研究较少。我们比较了医疗补助受益人与无精神疾病患者的乳腺癌结局。
使用 1996 年至 2005 年俄亥俄癌症发病率监测系统(OCISS)和医疗补助档案记录,我们确定了年龄<65 岁、接受过浸润性乳腺癌治疗、在癌症诊断前至少有 3 个月接受过医疗补助的自费女性(n=2177)。我们从 OCISS 中获取癌症分期、患者人口统计学和居住地信息。从医疗补助索赔数据中,我们根据程序代码确定乳腺癌治疗方法,根据诊断代码、处方药物和服务代码确定精神疾病状态。我们开发了逻辑回归模型,以检查精神疾病、癌症分期和局部区域疾病治疗之间的关联,同时调整潜在混杂因素。
患有精神疾病的女性占研究人群的 60.2%。调整潜在混杂因素后,患有精神疾病的女性未分期或未知分期癌症的可能性低于无精神疾病的女性(调整后的优势比[OR],0.61;95%可信区间[CI],0.44 至 0.86;P=0.005),且患有远处分期癌症的可能性也较低(调整后的 OR,0.59;95%CI,0.40 至 0.85;P=0.005)。我们没有观察到精神疾病状态对局部区域疾病确定性治疗的影响(调整后的 OR,1.04;95%CI,0.84 至 1.29;P=0.08)。
在俄亥俄州医疗补助受益人中,患有精神疾病的女性在乳腺癌分期或局部区域疾病治疗方面没有差异。这些发现可能反映了医疗补助的均衡作用,通过为弱势群体提供更多的身心健康保健服务,改善了他们的医疗可及性。