Centre for Developmental Health, Curtin University of Technology and Telethon Institute for Child Health Research, Perth, Australia.
Can J Psychiatry. 2010 Dec;55(12):752-60. doi: 10.1177/070674371005501202.
to investigate the burden of excess mortality among people with mental illness in developed countries, how it is distributed, and whether it has changed over time.
we conducted a systematic search of MEDLINE, restricting our attention to peer-reviewed studies and reviews published in English relating to mortality and mental illness. Because of the large number of studies that have been undertaken during the last 30 years, we have selected a representative cross-section of studies for inclusion in our review.
there is substantial excess mortality in people with mental illness for almost all psychiatric disorders and all main causes of death. Consistently elevated rates have been observed across settings and over time. The highest numbers of excess deaths are due to cardiovascular and respiratory diseases. With life expectancy increasing in the general population, the disparity in mortality outcomes for people with mental illness is increasing.
without the development of alternative approaches to promoting and treating the physical health of people with mental illness, it is possible that the disparity in mortality outcomes will persist.
调查发达国家精神疾病患者的超额死亡率负担，其分布情况以及随时间的变化。
我们对 MEDLINE 进行了系统检索，仅关注以英语发表的与死亡率和精神疾病相关的同行评审研究和综述。由于过去 30 年来进行了大量研究，因此我们选择了有代表性的研究横断面纳入我们的综述。
几乎所有精神障碍和所有主要死因的精神疾病患者的死亡率都存在大量的超额死亡。在不同的环境和不同的时间，死亡率一直呈上升趋势。因心血管疾病和呼吸系统疾病而导致的超额死亡人数最多。随着普通人群预期寿命的延长，精神疾病患者的死亡率差异也在增加。
如果不开发促进和治疗精神疾病患者身体健康的替代方法，死亡率结果的差异可能会持续存在。
