Eghbalian F
Pediatric Department, Hamadan University of Medical Sciences, Hamedan, Iran.
J Neonatal Perinatal Med. 2014;7(4):273-7. doi: 10.3233/NPM-14814049.
Respiratory distress syndrome (RDS) is one of the most important causes of mortality and morbidity in premature newborns. The aim of this study was to determine the effect of body position on oxygen saturation in hospitalized premature infants with RDS.
From June 2010 to December 2012, 69 premature infants with RDS were evaluated in an interventional analytic study. Patients had a mean gestational age (±SD) of 31.4 (±2.41) weeks (range: 28-35 weeks) with a mean birth weight (±SD) of 1446.6 (±218.90) grams (range: 850-2400 grams). Infants were studied both in supine and in prone positions. Oxygen saturation was monitored by trans-cutaneous pulse oximeter and oxygen saturation was continually monitored for 3 hours in each position and mean oxygen saturation was calculated at the end of each 3 hour period. All patients were premature, NPO, oxygen dependent and had RDS. The range of the postnatal age of the studied infants was 24-48 hr.
Means (±SD) of oxygen saturation during 3 hours in prone and supine positions were 92.54% (±2.24%) and 91.78% (±2.35%), respectively (p = 0.001). Also means (±SD) of oxygen saturation at the end of each 3-hours period prone and supine positions were 91.30% (±2.42%) and 90.30% (±3.15%), respectively (p = 0.006).
These findings suggest that, in premature infants with RDS, oxygen saturation was significantly higher in the prone compared with the supine posture.
呼吸窘迫综合征(RDS)是早产新生儿死亡和发病的最重要原因之一。本研究的目的是确定体位对住院的RDS早产婴儿血氧饱和度的影响。
在一项干预性分析研究中,对2010年6月至2012年12月期间的69例RDS早产婴儿进行了评估。患者的平均胎龄(±标准差)为31.4(±2.41)周(范围:28 - 35周),平均出生体重(±标准差)为1446.6(±218.90)克(范围:850 - 2400克)。对婴儿分别进行仰卧位和俯卧位研究。通过经皮脉搏血氧仪监测血氧饱和度,在每个体位持续监测3小时的血氧饱和度,并在每3小时时段结束时计算平均血氧饱和度。所有患者均为早产、非经口进食、依赖氧气且患有RDS。研究婴儿的出生后年龄范围为24 - 48小时。
俯卧位和仰卧位3小时期间血氧饱和度的平均值(±标准差)分别为92.54%(±2.24%)和91.78%(±2.35%)(p = 0.001)。同样,俯卧位和仰卧位每3小时时段结束时血氧饱和度的平均值(±标准差)分别为91.30%(±2.42%)和90.30%(±3.15%)(p = 0.006)。
这些发现表明,患有RDS的早产婴儿,俯卧位时的血氧饱和度明显高于仰卧位。