Guiloff R J
Department of Neurology, Westminster Hospital, London.
J R Soc Med. 1989 May;82(5):278-80. doi: 10.1177/014107688908200511.
Twenty six (41%) of 64 central London cases of AIDS with nervous system involvement during the course of the illness had neurological opportunist infection. Cytomegalovirus and Toxoplasma gondii were the commonest agents in 22 cases with central nervous system (CNS) infection. Eight cases had herpes zoster radiculopathy. Other infections included those caused by Cryptococcus neoformans, Mycobacterium tuberculosis and papova JC virus. Prognosis was generally poor, irrespective of whether the opportunist infection was treatable.
在伦敦市中心64例病程中出现神经系统受累的艾滋病患者中,有26例(41%)发生了神经系统机会性感染。巨细胞病毒和弓形虫是22例中枢神经系统(CNS)感染中最常见的病原体。8例患有带状疱疹性神经根病。其他感染包括新型隐球菌、结核分枝杆菌和乳头多瘤空泡病毒JC型引起的感染。无论机会性感染是否可治,预后通常都很差。