Rodríguez Zaydalee Cardona, Ramos Michelle González
Bol Asoc Med P R. 2014;106(3):29-31.
Acremonium species are filamentous, cosmopolitan fungi frequently isolated from plant debris and soil that have emerged as an important cause of morbidity and mortality in immunocompromised patients. We present data from two hematologic malignancy patients with Acremonium fungemia who had refractory disease despite initial treatment with Amphotericin B with clinical response after changing therapy to Voriconazole. Acremonium should be considered in the differential diagnosis of patients with clinical presentation suggestive of fungal infection and special attention should be given to the treatment challenge it represents.
枝顶孢属真菌是丝状的、遍布全球的真菌，常从植物残体和土壤中分离出来，已成为免疫功能低下患者发病和死亡的重要原因。我们报告了两名患有枝顶孢菌血症的血液系统恶性肿瘤患者的数据，他们在最初接受两性霉素B治疗时病情难治，在将治疗改为伏立康唑后出现临床反应。对于临床表现提示真菌感染的患者，在鉴别诊断中应考虑枝顶孢菌，并且应特别关注它所带来的治疗挑战。
