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造血细胞移植病房中不常见的棘孢木霉真菌血症聚集。

An unusual cluster of Acremonium kiliense fungaemias in a haematopoietic cell transplantation unit.

机构信息

First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Diagn Microbiol Infect Dis. 2013 Mar;75(3):313-6. doi: 10.1016/j.diagmicrobio.2012.11.015. Epub 2013 Jan 3.

Abstract

The genus Acremonium (formerly known as Cephalosporium) is a large polyphyletic fungal genus that comprises approximately 150 phylogenetically distant species, commonly isolated from the environment. Clinical cases concern mostly superficial infections after traumatic inoculation, but there are reports of opportunistic invasive infections in immunocompromised patients. Acremonium kiliense has been described as a cause of mycetoma, keratitis, endophthalmitis, endocarditis, and continuous ambulatory peritoneal dialysis-associated peritonitis. We describe an unusual cluster of possible catheter-related bloodstream infections due to this pathogen in patients who underwent haematopoietic cell transplantation.

摘要

棘孢木霉属(以前称为头状头孢霉属)是一个大型多系真菌属,包含约 150 个在系统发育上相距较远的种,通常从环境中分离出来。临床病例主要涉及创伤性接种后的浅表感染,但也有免疫功能低下患者发生机会性侵袭性感染的报告。棘孢木霉已被描述为足菌肿、角膜炎、眼内炎、心内膜炎和持续性非卧床腹膜透析相关性腹膜炎的病因。我们描述了造血细胞移植患者中因这种病原体引起的可能与导管相关的血流感染的不常见聚集性病例。

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