Malhotra Chintan, Jain Arun K, Sawhney Ashish, Nawani Nishant, Ram Jagat
Advanced Eye Centre, Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Cornea. 2015 Feb;34(2):193-8. doi: 10.1097/ICO.0000000000000318.
The aim of this study was to compare the recurrence rates for primary pterygia after fibrin glue-assisted conjunctival autograft (CAG) versus conjunctivolimbal autograft (CLAG) transplantation, using a technique of limited conjunctival resection and Tenon extended removal.
In this comparative case series, 49 eyes of 47 patients with primary nasal pterygium were included. Patients were randomized into 2 groups to undergo fibrin glue-assisted CAG (group 1, 24 eyes) or fibrin glue-assisted CLAG (group 2, 25 eyes) following excision of pterygium. The surgical technique used in all patients involved limited conjunctival resection combined with extensive removal of the Tenon capsule up to the caruncle medially and also 5 mm beyond the inferior and superior free edges of the conjunctiva. The main outcome measure studied was the absence or presence of recurrence.
There was 0% recurrence rate in both groups after a mean follow-up of 63 weeks (range, 54-81 weeks) with all eyes completing at least 1-year of follow-up.
Fibrin glue-assisted CAG and CLAG using the technique of conjunctival resection and Tenon extended removal were equally efficacious in terms of preventing recurrences in patients with primary pterygia in our series.
本研究旨在比较纤维蛋白胶辅助结膜自体移植(CAG)与结膜角膜缘自体移植(CLAG)治疗原发性翼状胬肉后的复发率,采用有限结膜切除联合Tenon囊扩大切除技术。
在这个比较性病例系列中,纳入了47例原发性鼻侧翼状胬肉患者的49只眼。患者被随机分为2组,在翼状胬肉切除后分别接受纤维蛋白胶辅助CAG(第1组,24只眼)或纤维蛋白胶辅助CLAG(第2组,25只眼)。所有患者采用的手术技术包括有限结膜切除,联合向内侧直至泪阜并超出结膜上下游离缘5 mm广泛切除Tenon囊。研究的主要结局指标是有无复发。
平均随访63周(范围54 - 81周),所有眼均完成至少1年的随访,两组复发率均为0%。
在我们的系列研究中,采用结膜切除联合Tenon囊扩大切除技术的纤维蛋白胶辅助CAG和CLAG在预防原发性翼状胬肉患者复发方面同样有效。