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原发性翼状胬肉中使用纤维蛋白胶的角膜缘结膜自体移植术的最佳翼状胬肉切除大小。

Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia.

作者信息

Hwang Ho Sik, Cho Kyong Jin, Rand Gabriel, Chuck Roy S, Kwon Ji Won

机构信息

Department of Ophthalmology, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, Korea.

Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea.

出版信息

BMC Ophthalmol. 2018 Jun 7;18(1):135. doi: 10.1186/s12886-018-0790-6.

Abstract

BACKGROUND

In our study we describe a method that optimizes size of excision and autografting for primary pterygia along with the use of intraoperative MMC and fibrin glue. Our objective is to propose a simple, optimizedpterygium surgical technique with excellent aesthetic outcomes and low rates of recurrence and otheradverse events.

METHODS

Retrospective chart review of 78 consecutive patients with stage III primary pterygia who underwent an optimal excision technique by three experienced surgeons. The technique consisted of removal of the pterygium head, excision of the pterygium body and Tenon's layer limited in proportion to the length of the head, application of intraoperative mitomycin C to the defect, harvest of superior bulbar limbal conjunctival graft, adherence of graft with fibrin glue. Outcomes included operative time, follow up period, pterygium recurrence, occurrences of incorrectly sized grafts, and other complications.

RESULTS

All patients were followed up for more than a year. Of the 78 patients, there were 2 cases of pterygium recurrence (2.6%). There was one case of wound dehiscence secondary to small-sized donor conjunctivaand one case of over-sized donor conjunctiva, neither of which required surgical correction. There were no toxic complications associated with the use of mitomycin C.

CONCLUSION

Correlating the excision of the pterygium body and underlying Tenon's layer to the length of the pterygium head, along with the use intraoperative mitomycin C, limbal conjunctival autografting, and fibrin adhesionresulted in excellent outcomes with a low rate of recurrence for primary pterygia.

摘要

背景

在我们的研究中,我们描述了一种优化原发性翼状胬肉切除和自体移植大小的方法,同时使用术中丝裂霉素C和纤维蛋白胶。我们的目标是提出一种简单、优化的翼状胬肉手术技术,具有出色的美学效果、低复发率和其他不良事件发生率。

方法

对78例连续的III期原发性翼状胬肉患者进行回顾性病历审查,这些患者由三位经验丰富的外科医生采用最佳切除技术进行治疗。该技术包括切除翼状胬肉头部、按与头部长度成比例限制切除翼状胬肉体和Tenon囊,术中向缺损处应用丝裂霉素C,取上方球结膜缘移植片,用纤维蛋白胶固定移植片。结果包括手术时间、随访期、翼状胬肉复发、移植片大小不合适的发生率以及其他并发症。

结果

所有患者均随访超过一年。78例患者中,有2例翼状胬肉复发(2.6%)。有1例因供体结膜过小导致伤口裂开,1例供体结膜过大,均无需手术矫正。使用丝裂霉素C未出现毒性并发症。

结论

将翼状胬肉体和下方Tenon囊的切除与翼状胬肉头部的长度相关联,同时使用术中丝裂霉素C、角膜缘结膜自体移植和纤维蛋白粘连,可使原发性翼状胬肉获得良好的治疗效果,复发率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d80/5992752/a4e39e13ad84/12886_2018_790_Fig1_HTML.jpg

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