Fieo Robert, Mukherjee Shubhabrata, Dmitrieva Natalia O, Fyffe Denise C, Gross Alden L, Sanders Elizabeth R, Romero Heather R, Potter Guy G, Manly Jennifer J, Mungas Dan M, Gibbons Laura E
Cognitive Neuroscience Division, Department of Neurology and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, USA.
General Internal Medicine, University of Washington, Seattle, WA, USA.
Int J Geriatr Psychiatry. 2015 Sep;30(9):911-8. doi: 10.1002/gps.4234. Epub 2014 Dec 5.
The objective of this study is to determine whether differential item functioning (DIF) due to cognitive status impacted three depressive symptoms measures commonly used with older adults.
Differential item functioning in depressive symptoms was assessed among participants (N = 3558) taking part in four longitudinal studies of cognitive aging, using the Geriatric Depression Scale, the Montgomery-Åsberg Depression Rating Scale, and the Center for Epidemiologic Studies Depression Scale. Participants were grouped by cognitive status using a general cognitive performance score derived from each study's neuropsychological battery and linked to a national average using a population-based survey representative of the US population. The Clinical Dementia Rating score was used as an alternate grouping variable in three of the studies.
Although statistically significant DIF based on cognitive status was found for some depressive symptom items (e.g., items related to memory complaints, appetite loss, lack of energy, and mood), the effect of item bias on the total score for each scale was negligible.
The depressive symptoms scales in these four studies measured depression in the same way, regardless of cognitive status. This may reduce concerns about using these depression measures in cognitive aging research, as relationships between depression and cognitive decline are unlikely to have been due to item bias, at least in the ways that were measured in the datasets we considered.
本研究的目的是确定认知状态导致的项目功能差异(DIF)是否会影响老年人常用的三种抑郁症状测量方法。
在参与四项认知老化纵向研究的参与者(N = 3558)中,使用老年抑郁量表、蒙哥马利-Åsberg抑郁评定量表和流行病学研究中心抑郁量表评估抑郁症状的项目功能差异。参与者根据认知状态进行分组,使用从每项研究的神经心理测验电池得出的一般认知表现分数,并通过代表美国人口的基于人群的调查与全国平均水平相联系。在三项研究中,临床痴呆评定分数被用作替代分组变量。
尽管在某些抑郁症状项目(例如与记忆问题、食欲减退、缺乏精力和情绪相关的项目)中发现了基于认知状态的具有统计学意义的项目功能差异,但项目偏差对每个量表总分的影响可以忽略不计。
这四项研究中的抑郁症状量表以相同的方式测量抑郁,无论认知状态如何。这可能会减少在认知老化研究中使用这些抑郁测量方法的担忧,因为抑郁与认知衰退之间的关系不太可能是由于项目偏差,至少在我们所考虑的数据集中测量的方式上是这样。