[百日咳博德特氏菌的致白血病作用]
[The coleukemogenic action of Bordetella pertussis].
作者信息
Shevliagin V Ia, Shaposhnikova G M, Snegireva A E, Mertsalova N U
出版信息
Eksp Onkol. 1989;11(4):50-2.
PMID:2547574
Abstract
Injection of B. pertussis and Rauscher leukemia virus (RLV) in a dose of 4 ID50 to BALB/c mice susceptible to the above virus significantly increases the incidence of leukosis and shortens the average life duration. Injection of B. pertussis to the AKR mice, carriers of the Gross leukosis virus, induces in the first months a greater number of the mice with leukosis and its earlier development.
摘要
向对上述病毒敏感的BALB/c小鼠注射剂量为4个半数感染量（ID50）的百日咳杆菌和劳氏肉瘤病毒（RLV），可显著增加白血病的发病率并缩短平均寿命。向携带格罗斯白血病病毒的AKR小鼠注射百日咳杆菌，在最初几个月会使更多小鼠患白血病，且白血病发展得更早。
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