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阿立哌唑成功治疗抽动秽语综合征的病例报告。

Case report on Tourette syndrome treated successfully with aripiprazole.

作者信息

Bhatia Ms, Gautam Priyanka, Kaur Jaswinder

机构信息

Department of Psychiatry, University of Medical Sciences, Guru Teg Bahadur Hospital, Delhi, India.

出版信息

Shanghai Arch Psychiatry. 2014 Oct;26(5):297-9. doi: 10.11919/j.issn.1002-0829.214120.

DOI:10.11919/j.issn.1002-0829.214120
PMID:25477724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4248263/
Abstract

Tourette syndrome is a childhood-onset neuropsychiatric disorder characterized by multiple motor and vocal tics of at least one year in duration. This case report describes the history of a 16-year-old boy with a 6-year history of Tourette syndrome who was seriously disabled by his symptoms. Treatment with aripiprazole 10mg/d completely resolved his symptoms in about a month allowing him to return to the life that he had been missing because of his illness. In such cases the potential long-term negative effects of using antipsychotic medications need to weighed against the disruptive effects persistent Tourette symptoms can have on patient's lives.

摘要

抽动秽语综合征是一种起病于儿童期的神经精神障碍,其特征为多种运动性和发声性抽动,病程至少一年。本病例报告描述了一名患有抽动秽语综合征6年的16岁男孩的病史,其症状严重影响了他的生活。使用阿立哌唑10mg/d进行治疗,大约一个月后他的症状完全缓解,使他能够回归因疾病而失去的正常生活。在这类病例中,需要权衡使用抗精神病药物可能产生的长期负面影响与抽动秽语综合征持续症状对患者生活可能造成的干扰影响。

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引用本文的文献

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Safety of aripiprazole for tics in children and adolescents: A systematic review and meta-analysis.阿立哌唑治疗儿童和青少年抽动症的安全性:一项系统评价和荟萃分析。
Medicine (Baltimore). 2019 May;98(22):e15816. doi: 10.1097/MD.0000000000015816.

本文引用的文献

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European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment.欧洲抽动秽语综合征和其他抽动障碍临床指南。第二部分:药物治疗。
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Recent advances in Tourette syndrome.抽动秽语综合征的最新进展。
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Neurobiological substrates of Tourette's disorder.抽动秽语综合征的神经生物学基础。
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