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对一名患有帕金森病和中度抑郁症患者的电休克治疗。

Electroconvulsive treatment of a patient with Parkinson's disease and moderate depression.

作者信息

Berg John E

机构信息

Blakstad Hospital, Vestre Viken Hospital Trust, Asker, Norway.

出版信息

Ment Illn. 2011 May 19;3(1):e3. doi: 10.4081/mi.2011.e3. eCollection 2011 Feb 22.

DOI:10.4081/mi.2011.e3
PMID:25478095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4253360/
Abstract

Depression is a usual comorbidity in patients with Parkinson's disease. It has been known for more than 50 years that electroconvulsive treatment (ECT) has a positive effect on the muscular symptoms of Parkinson's disease. Many countries do not allow giving ECT for this indication. We have recently treated a resident patient in an acute psychiatric facility referred to the hospital with moderate depressive symptoms and strong suicidal ideation. Before and after a series of ECT he filled out the Beck Depression Inventory and the Antonovsky Sense of Coherence test. The scores before ECT were 20 and 2.69, respectively, and after 12 treatments 14 and 3.38. Both test results indicate improvement regarding level of depression and coping in life. The physiotherapists treating him observed that his rigidity was reduced and his gait improved. Muscular tonus was reduced and increased his tendency of falling as he had less tonus in muscles close to joints. Self help efficiency in daily tasks improved. He got cognitive impairment during and in the weeks after ECT. Electroconvulsive treatment should be offered to more patients with Parkinson disease and depression in order to lessen the burden of both depression and Parkinson symptoms.

摘要

抑郁症是帕金森病患者常见的共病。50多年来,人们一直知道电休克治疗(ECT)对帕金森病的肌肉症状有积极作用。许多国家不允许针对这一适应症进行ECT治疗。我们最近在一家急性精神病院治疗了一名住院患者,该患者因中度抑郁症状和强烈的自杀意念被转诊至我院。在一系列ECT治疗前后,他填写了贝克抑郁量表和安托诺夫斯基连贯感测试。ECT治疗前的分数分别为20和2.69,经过12次治疗后为14和3.38。两项测试结果均表明抑郁水平和应对生活的能力有所改善。治疗他的物理治疗师观察到他的僵硬程度减轻,步态有所改善。肌肉紧张度降低,由于关节附近肌肉的紧张度降低,他摔倒的倾向增加。日常任务中的自助效率提高。他在ECT治疗期间及治疗后的几周出现了认知障碍。应该为更多患有帕金森病和抑郁症的患者提供电休克治疗,以减轻抑郁和帕金森症状的负担。

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本文引用的文献

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Ment Illn. 2010 Feb 11;2(1):e3. doi: 10.4081/mi.2010.e3. eCollection 2010 Jan 25.
2
Marked improvement of psychotic symptoms after electroconvulsive therapy in Parkinson disease.帕金森病患者电抽搐治疗后精神病症状明显改善。
J ECT. 2010 Jun;26(2):111-5. doi: 10.1097/YCT.0b013e3181c18a3d.
3
Occurrence and risk factors for apathy in Parkinson disease: a 4-year prospective longitudinal study.帕金森病中淡漠的发生率及危险因素:一项为期4年的前瞻性纵向研究。
J Neurol Neurosurg Psychiatry. 2009 Nov;80(11):1279-82. doi: 10.1136/jnnp.2008.170043.
4
Suicide in young Norwegians in a life course perspective: population-based cohort study.从人生历程角度看挪威年轻人的自杀问题:基于人群的队列研究。
J Epidemiol Community Health. 2010 May;64(5):407-12. doi: 10.1136/jech.2008.083485. Epub 2009 Aug 13.
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ECT for Parkinson's disease.用于帕金森病的电休克治疗
Med Hypotheses. 2009 Oct;73(4):468-9. doi: 10.1016/j.mehy.2009.06.053. Epub 2009 Aug 5.
6
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Int J Psychiatry Med. 2009;39(1):101-12. doi: 10.2190/PM.39.1.h.
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Dopamine Agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study.多巴胺激动剂及其在帕金森病中诱发精神病性发作的风险:一项病例对照研究。
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