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在“惊恐障碍管理的生活方式方法”研究中对惊恐障碍的常规全科医疗护理。

Routine general practice care for panic disorder within the lifestyle approach to managing panic study.

作者信息

Lambert Rodney A

机构信息

Faculty of Medicine and Health, University of East Anglia, Norwich, UK.

出版信息

Ment Illn. 2012 Sep 6;4(2):e18. doi: 10.4081/mi.2012.e18. eCollection 2012 Jul 26.

Abstract

UNLABELLED

Routine general practice (GP) care is rarely comprehensively described in clinical trials. This paper examines routine GP care within the lifestyle approach to managing panic (LAMP) study. The aim of this paper is to describe/discuss routine GP care for panic disorder (PD) patients within both study arms in the LAMP study. An unblinded pragmatic randomised controlled trial in 15 East of England GP practices (2 primary care trusts). Participants met Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for PD with/without agoraphobia. Follow-up measures recorded at 20 weeks/10 months following randomisation. Control arm, unrestricted routine GP care (practice appointments, referrals and prescriptions). Trial arm, occupational therapy-led lifestyle treatment comprising lifestyle review of fluid intake, diet pattern, exercise, caffeine, alcohol and nicotine.

PRIMARY OUTCOME MEASURE

beck anxiety inventory. At baseline, participants attended 2-3 times more GP appointments than population average, reducing at 10 months to 1.6 times population average for routine GP care and 0.97 population average for lifestyle arm. At 10 months, 33% fewer referrals (6 referrals; 0 mental health) than at baseline (9 referrals; 2 mental health) were made for lifestyle arm patients compared with 42% increase (from 12 referrals; 8 mental health at baseline to 17 referrals; 7 mental health) in GP care arm. Selective serotonin reuptake inhibitors were prescribed most often. Benzodiazepines and beta-blockers were prescribed more often than tricyclic against current clinical guidelines. In conclusion, we found that PD patients at baseline were high healthcare resource users. Treatment in both study arms reduced resource use. Routine GP care requires further review for this patient group.

摘要

未标注

临床试验中很少全面描述常规全科医疗(GP)护理。本文研究了管理惊恐障碍(LAMP)研究中生活方式方法下的常规GP护理。本文旨在描述/讨论LAMP研究中两个研究组内惊恐障碍(PD)患者的常规GP护理。在英格兰东部15个GP诊所(2个初级医疗信托机构)进行的一项非盲实用随机对照试验。参与者符合《精神障碍诊断与统计手册》第四版中有无广场恐惧症的PD标准。随机分组后20周/10个月记录随访措施。对照组,不受限制的常规GP护理(诊所预约、转诊和处方)。试验组,由职业治疗主导的生活方式治疗,包括对液体摄入、饮食模式、运动、咖啡因、酒精和尼古丁的生活方式评估。

主要结局指标

贝克焦虑量表。基线时,参与者就诊GP诊所的次数比人群平均水平多2至3倍,在10个月时,常规GP护理组降至人群平均水平的1.6倍,生活方式组降至0.97倍。在10个月时,生活方式组患者的转诊次数(6次转诊;0次心理健康转诊)比基线时(9次转诊;2次心理健康转诊)减少了33%,而GP护理组增加了42%(从基线时的12次转诊;8次心理健康转诊增至17次转诊;7次心理健康转诊)。最常开具的是选择性5-羟色胺再摄取抑制剂。与当前临床指南相比,苯二氮䓬类药物和β受体阻滞剂的处方频率高于三环类药物。总之,我们发现基线时的PD患者是高医疗资源使用者。两个研究组的治疗均减少了资源使用。对于该患者群体,常规GP护理需要进一步审查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6dc/4253376/f0925921b9d9/mi-2012-2-e18-g001.jpg

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