School of Allied Health Professions, University of East Anglia, Norwich, UK.
Soc Psychiatry Psychiatr Epidemiol. 2010 Jul;45(7):741-50. doi: 10.1007/s00127-009-0114-5. Epub 2009 Aug 18.
To assess the cost-effectiveness of an occupational therapy-led lifestyle approach to treating panic disorder in primary care compared with routine general practitioner's (GP) care. The burden of mental health disorders is considerable. Cost-effective interventions are necessary to alleviate some of these burdens. Habitual lifestyle behaviours influence mood, although to date mainly single lifestyle factor trials have been conducted to examine the effects on anxiety.
An economic evaluation was conducted alongside an unblinded pragmatic randomised controlled trial with assessment at 5 and 10 months. Costs and consequences, as measured by the Beck anxiety inventory (BAI) and quality adjusted life years (QALYs), were compared using incremental cost-effectiveness ratios (ICERs).
The occupational therapy-led lifestyle intervention was more costly than routine GP care at both 5 and 10 months. Significant outcome improvements were evident at 5 months when using the BAI, although these were not maintained at 10 months. Small differences in mean QALYs were found. The estimated ICER was 36 pounds per BAI improvement for 5 months and 39 pounds for 10 months, and 18,905 pounds per QALY gained for 5 months and 8,283 pounds for 10 months.
If the maximum willingness to pay per additional QALY is 30,000 pounds, then there is an 86% chance that a lifestyle intervention may be considered to be value-for-money over 10 months.
评估职业治疗主导的生活方式方法在初级保健中治疗惊恐障碍的成本效益,与常规全科医生(GP)护理相比。心理健康障碍的负担相当大。需要具有成本效益的干预措施来减轻其中的一些负担。习惯性的生活方式行为会影响情绪,尽管迄今为止,主要进行了单一生活方式因素试验来研究对焦虑的影响。
在一项非盲随机对照试验中进行了经济评估,并在 5 个月和 10 个月时进行了评估。使用贝克焦虑量表(BAI)和质量调整生命年(QALYs)来衡量成本和结果,使用增量成本效益比(ICER)进行比较。
职业治疗主导的生活方式干预在 5 个月和 10 个月时均比常规 GP 护理花费更高。在使用 BAI 时,在 5 个月时出现了明显的结果改善,尽管在 10 个月时没有得到维持。在平均 QALYs 方面发现了微小差异。估计的 ICER 分别为 5 个月时 BAI 改善 36 英镑,10 个月时 39 英镑,5 个月时 QALY 增加 18,905 英镑,10 个月时增加 8,283 英镑。
如果每个额外 QALY 的最高意愿支付为 30,000 英镑,那么在 10 个月内,生活方式干预可能被认为是物有所值的可能性为 86%。