Hammodi Adel, Al-Azem M Ali, Hanafy Ahmed, Nakkar Talal
King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi Arabia.
Critical Care Department, King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi Arabia.
Case Rep Crit Care. 2014;2014:231081. doi: 10.1155/2014/231081. Epub 2014 Nov 13.
Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot-not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.
肺栓塞（PE）是住院患者发病和死亡的常见原因。恶性肿瘤、长期卧床和化疗是临床上显著PE发生的著名危险因素。癌症会引发多种病理生理过程，例如高凝状态和血管异常伴循环缓慢，进而可能导致PE。肿瘤细胞的一个独特特征是它们能够进入循环系统并表现为血凝块——而非转移灶——阻塞肺循环。我们报告一例经组织学诊断为肿瘤细胞栓塞导致的致命性肺栓塞病例。
