Fatima Uroos, Sherwani Rana, Khan Tamkin, Zaheer Sufian
Associate Professor, Department of Pathology, DMWayanad Institute of Medical Sciences , Naseera Nagar, Mepaddi, Wayanad, Kerala, India .
Professor, Department of Pathology, Jawahar Lal Nehru Medical College, AMU , Aligarh, Uttar Pradesh, India .
J Clin Diagn Res. 2014 Oct;8(10):FC05-8. doi: 10.7860/JCDR/2014/9226.4920. Epub 2014 Oct 20.
Intrauterine death(IUD)/ Stillbirth forms a major part of perinatal mortality which thereby is a good indicator of pregnancy wastage as well as quality of healthcare available. The key objectives of autopsy examination are to know the cause(s) of death, elucidation of pathogenic mechanism and quality control of clinical management. The aim of this study was to identify the prevalent causes of IUD, thereby taking appropriate measures to prevent them and decrease the perinatal mortality rate.
The study included 14 cases of IUD received for autopsy in the Department of Pathology over a period of five years. Autopsies were performed as per standard protocol and included full anthropometric profile, external examination, gross and microscopic evaluation of different organs and placenta.
Total number of 14 fetal autopsies were performed over a period of 5 years. The causes were broadly classified as fetal, maternal and placental. Placental causes were seen in majority of cases (48.57%) followed by fetal (35.72%) and then maternal (21.42). Most prevalent cause of death was congenital anomalies (28.6%) followed by placental insufficiency (21.4%) and chorioamnionitis (14.2%).
Determination of causes of fetal death would prove beneficial to the clinicians and parents for better management and care in future pregnancies as well as in genetic counseling.
死胎/死产是围产期死亡率的主要组成部分,因此是妊娠丢失以及现有医疗保健质量的良好指标。尸检的主要目的是了解死亡原因、阐明致病机制以及临床管理的质量控制。本研究的目的是确定死胎的常见原因,从而采取适当措施预防这些原因并降低围产期死亡率。
该研究纳入了病理学系在五年期间接收进行尸检的14例死胎病例。按照标准方案进行尸检,包括完整的人体测量、外部检查、对不同器官和胎盘的大体及显微镜评估。
在5年期间共进行了14例胎儿尸检。原因大致分为胎儿、母体和胎盘原因。大多数病例(48.57%)为胎盘原因,其次是胎儿原因(35.72%),然后是母体原因(21.42%)。最常见的死亡原因是先天性异常(28.6%),其次是胎盘功能不全(21.4%)和绒毛膜羊膜炎(14.2%)。
确定胎儿死亡原因将证明对临床医生和父母在未来妊娠的更好管理和护理以及遗传咨询方面有益。