Pailoor Kirana, Fernandes Hilda, Cs Jayaprakash, Marla Nisha J, Keshava S Murali
Associate Professor, Department of Pathology, Father Muller Medical College , Mangalore, India .
Professor and Head, Department of Pathology, Father Muller Medical College , Mangalore, India .
J Clin Diagn Res. 2014 Oct;8(10):FC13-5. doi: 10.7860/JCDR/2014/10708.4922. Epub 2014 Oct 20.
Fine needle aspiration cytology (FNAC) has a well-established role in the management of palpable breast lumps. However breast masses in males are rarely aspirated and hence there is limited cytopathologic experience. The aim of our study was to determine the efficacy of FNAC in the diagnosis of male breast lesions and also we attempted to describe the cytomorphological features of some of these lesions.
Data on male breast FNAC done between 2008 to 2013 were retrieved from the records of the cytopathology laboratory. FNAC diagnosis were categorized as benign, malignant, suspicious for malignancy and inadequate or unsatisfactory. Cytohistologic correlation was done with data from histopathology records. Sensitivity, specificity and diagnostic accuracy were calculated using standard statistical methods.
Forty out of 1098 patients undergoing breast FNAC were males. Histopathology was available in 8 (20%) out of 40 cases. There were no false positive or false negative diagnoses. FNAC had a sensitivity, specificity and diagnostic accuracy of 100% for male breast lesions.
FNAC is a very accurate tool for the diagnosis of male breast lesions. It is highly sensitive and specific with good cytohistologic correlation. To reduce the high rate of surgical biopsies of benign male breast masses, we conclude that FNAC should be performed as a standard procedure in the clinical evaluation of male breast lesions.
细针穿刺细胞学检查（FNAC）在可触及乳腺肿块的处理中具有既定作用。然而，男性乳腺肿块很少进行穿刺，因此细胞病理学经验有限。我们研究的目的是确定FNAC在男性乳腺病变诊断中的有效性，并且我们试图描述其中一些病变的细胞形态学特征。
从细胞病理学实验室记录中检索2008年至2013年期间进行的男性乳腺FNAC数据。FNAC诊断分为良性、恶性、可疑恶性以及不充分或不满意。将细胞病理学结果与组织病理学记录数据进行相关性分析。使用标准统计方法计算敏感性、特异性和诊断准确性。
1098例接受乳腺FNAC检查的患者中有40例为男性。40例中有8例（20%）有组织病理学结果。没有假阳性或假阴性诊断。FNAC对男性乳腺病变的敏感性、特异性和诊断准确性均为100%。
FNAC是诊断男性乳腺病变的非常准确的工具。它具有高度敏感性和特异性，细胞病理学与组织病理学相关性良好。为降低良性男性乳腺肿块的高手术活检率，我们得出结论，FNAC应作为男性乳腺病变临床评估的标准程序进行。
